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热烧伤中的真菌感染:在一家三级护理中心的前瞻性研究。

Fungal Infection in Thermal Burns: A Prospective Study in a Tertiary Care Centre.

作者信息

Sharma Sanjeev, Bajaj Deepak, Sharma Pritika

机构信息

Associate Professor, Department of Surgery, Government Medical College , Amritsar, Punjab, India .

Junior Resident, Department of Surgery, Government Medical College , Amritsar, Punjab, India .

出版信息

J Clin Diagn Res. 2016 Sep;10(9):PC05-PC07. doi: 10.7860/JCDR/2016/20336.8445. Epub 2016 Sep 1.

Abstract

INTRODUCTION

Burn Wound Infection (BWI) is primarily caused by aerobic bacteria followed by fungi, anaerobes and viruses. There has been a worldwide decrease in incidence of bacterial infections in burns due to better patient care and availability of effective antibiotics. Consequently, the fungal burn wound infection has shown an increasing trend.

AIM

The aim of study was to assess the frequency of fungal infections in thermal burn wounds with respect to age of wounds, total body surface involved, depth of burns and to assess common fungal pathogens.

MATERIALS AND METHODS

The study was conducted on 50 patients admitted with thermal burn wounds having 20-60% burns in the surgical unit. Pus swab and scrapings were taken under local anaesthesia from each burn patient. Scrapings were put in a sterile container and sent to Mycology section of Microbiology department and were examined by direct microscopy and culture studies on Sabouraud's Dextrose Agar medium in the Mycology section of Microbiology department.

RESULTS

In our study, the incidence of fungal infection in burn wound patients came out to be 26%. The incidence of fungal infection increased with increase in Total Body Surface Area, (TBSA) increase in depth and age of burn. In our study, the maximum positive fungal cultures were seen in the third week of post-burn period. No positive culture was seen in the first week and 30.76% positive fugal cultures were seen in second post-burn week. was found to be the most common organism followed by Non-albicans and .

CONCLUSION

It was concluded from the study that incidence of fungal infections in thermal burns increased with increase in post-burn period and with increasing depth and TBSA of burns. was found to be the most common fungus.

摘要

引言

烧伤创面感染(BWI)主要由需氧菌引起,其次是真菌、厌氧菌和病毒。由于患者护理水平提高以及有效抗生素的可获得性,全球范围内烧伤患者细菌感染的发生率有所下降。因此,真菌性烧伤创面感染呈上升趋势。

目的

本研究旨在评估热烧伤创面真菌感染的发生率与创面年龄、全身受累表面积、烧伤深度的关系,并评估常见真菌病原体。

材料与方法

本研究对50例因热烧伤创面入院、烧伤面积为20%-60%的患者在外科病房进行。在局部麻醉下从每位烧伤患者采集脓液拭子和刮屑。刮屑放入无菌容器中,送至微生物学系真菌学部门,在微生物学系真菌学部门通过直接显微镜检查和在沙氏葡萄糖琼脂培养基上进行培养研究。

结果

在我们的研究中,烧伤创面患者真菌感染的发生率为26%。真菌感染的发生率随着全身表面积(TBSA)、烧伤深度和烧伤年龄的增加而增加。在我们的研究中,烧伤后第三周真菌培养阳性率最高。烧伤后第一周未见阳性培养,烧伤后第二周真菌培养阳性率为30.76%。发现 是最常见的病原体,其次是非白色念珠菌和 。

结论

研究得出结论,热烧伤中真菌感染率随烧伤后时间、烧伤深度和TBSA的增加而增加。发现 是最常见的真菌。

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