[血脂作为缺血性心脏病遗传易感性的一个因素]
[Blood lipids as a factor of hereditary susceptibility to ischemic heart disease].
作者信息
Raĭkov A N, Khalfen E Sh, Koshechkin V A, Sokolova M A
出版信息
Kardiologiia. 1989 Jun;29(6):14-9.
PMID:2779072
Abstract
Examination of 166 families of the patients who had sustained myocardial infarction revealed aggregation of coronary heart disease in the families and the atherogenic shifts in the parameters of lipid turnover, which were caused by significant influences of genetic factors. The close relatives of the postinfarction patients were shown to display a large proportion of monogenic forms of hyperlipoproteinemias.
摘要
对166例心肌梗死患者的家族进行检查发现，这些家族中存在冠心病聚集现象，且脂质代谢参数出现致动脉粥样硬化变化，这些变化是由遗传因素的显著影响所致。心肌梗死后患者的近亲中显示出很大比例的单基因形式高脂蛋白血症。
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