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抗干扰素球蛋白可抑制出生时感染淋巴细胞性脉络丛脑膜炎病毒的小鼠肾小球肾炎的发展。

Anti-interferon globulin inhibits the development of glomerulonephritis in mice infected at birth with lymphocytic choriomeningitis virus.

作者信息

Gresser J, Morel-Maroger L, Verroust P, Rivière Y, Guillon J C

出版信息

Proc Natl Acad Sci U S A. 1978 Jul;75(7):3413-6. doi: 10.1073/pnas.75.7.3413.

DOI:10.1073/pnas.75.7.3413
PMID:277942
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC392787/
Abstract

Swiss mice infected at birth with lymphocytic choriomeningitis virus develop glomerulonephritis. Injection of potent anti-mouse interferon globulin at the time of viral infection inhibited the development of these renal lesions. We conclude that the production of endogenous interferon by this virus in the first few days of life plays an important role in the pathogenesis of this glomerulonephritis.

摘要

出生时感染淋巴细胞性脉络丛脑膜炎病毒的瑞士小鼠会患上肾小球肾炎。在病毒感染时注射强效抗小鼠干扰素球蛋白可抑制这些肾脏病变的发展。我们得出结论，该病毒在生命最初几天产生的内源性干扰素在这种肾小球肾炎的发病机制中起重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/392787/75f10c2a4193/pnas00019-0411-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/392787/0bb55034d63f/pnas00019-0411-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/392787/a7c79d2aa9f8/pnas00019-0411-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/392787/75f10c2a4193/pnas00019-0411-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/392787/0bb55034d63f/pnas00019-0411-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/392787/a7c79d2aa9f8/pnas00019-0411-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/392787/75f10c2a4193/pnas00019-0411-c.jpg

相似文献

1
Anti-interferon globulin inhibits the development of glomerulonephritis in mice infected at birth with lymphocytic choriomeningitis virus.抗干扰素球蛋白可抑制出生时感染淋巴细胞性脉络丛脑膜炎病毒的小鼠肾小球肾炎的发展。
Proc Natl Acad Sci U S A. 1978 Jul;75(7):3413-6. doi: 10.1073/pnas.75.7.3413.
2
Lymphocytic choriomeningitis infection in the nude mouse. An immunopathological study.裸鼠中的淋巴细胞性脉络丛脑膜炎感染。一项免疫病理学研究。
Immunology. 1981 Aug;43(4):763-70.
3
Severity of glomerulonephritis induced in different strains of suckling mice by infection with lymphocytic choriomeningitis virus: correlation with amounts of endogenous interferon and circulating immune complexes.淋巴细胞性脉络丛脑膜炎病毒感染诱导不同品系乳鼠发生肾小球肾炎的严重程度：与内源性干扰素量及循环免疫复合物的相关性
J Pathol. 1982 Dec;138(4):325-36. doi: 10.1002/path.1711380404.
4
Severity of lymphocytic choriomeningitis virus disease in different strains of suckling mice correlates with increasing amounts of endogenous interferon.淋巴细胞性脉络丛脑膜炎病毒病在不同品系乳鼠中的严重程度与内源性干扰素量的增加相关。
J Exp Med. 1980 Sep 1;152(3):633-40. doi: 10.1084/jem.152.3.633.
5
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Ann N Y Acad Sci. 1980;350:12-20. doi: 10.1111/j.1749-6632.1980.tb20602.x.
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Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. II. Relationship of the anti-lymphocytic choriomeningitis immune response to tissue injury in chronic lymphocytic choriomeningitis disease.与持续性淋巴细胞性脉络丛脑膜炎病毒感染相关的慢性疾病的发病机制。II. 慢性淋巴细胞性脉络丛脑膜炎疾病中抗淋巴细胞性脉络丛脑膜炎免疫反应与组织损伤的关系。
J Exp Med. 1970 Jan 1;131(1):1-19. doi: 10.1084/jem.131.1.1.
7
Glomerular lesions induced by interferon.干扰素诱导的肾小球病变
Transplant Proc. 1982 Sep;14(3):499-505.
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J Gen Virol. 1983 Aug;64 (Pt 8):1827-30. doi: 10.1099/0022-1317-64-8-1827.

引用本文的文献

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Perspect Med Virol. 1986;2:209-245. doi: 10.1016/S0168-7069(08)70043-0. Epub 2008 May 29.
2
A Brief Historical Perspective on the Pathological Consequences of Excessive Type I Interferon Exposure In vivo.体内过量暴露于I型干扰素的病理后果的简要历史回顾。
J Clin Immunol. 2018 Aug;38(6):694-698. doi: 10.1007/s10875-018-0543-6. Epub 2018 Sep 5.
3
Type I interferonopathies in pediatric rheumatology.儿童风湿病中的I型干扰素病

本文引用的文献

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GLOMERULONEPHRITIS AND LATE ONSET DISEASE OF MICE FOLLOWING NEONATAL VIRUS INFECTION.新生儿病毒感染后小鼠的肾小球肾炎和迟发性疾病
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EXPERIMENTS ON HETEROLOGOUS AND HOMOLOGOUS INTERFERENCE IN LCM-INFECTED CULTURES OF MURINE LYMPH NODE CELLS.鼠淋巴结细胞LCM感染培养物中异源和同源干扰的实验
Arch Gesamte Virusforsch. 1963 Oct 7;14:55-64. doi: 10.1007/BF01555163.
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Viral interference induced in mice by acute or persistent infection with the virus of lymphocytic choriomeningitis.
Pediatr Rheumatol Online J. 2016 Jun 4;14(1):35. doi: 10.1186/s12969-016-0094-4.
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Inhibition of the type I interferon antiviral response during arenavirus infection.沙粒病毒感染期间 I 型干扰素抗病毒反应的抑制。
Viruses. 2010 Nov;2(11):2443-80. doi: 10.3390/v2112443. Epub 2010 Nov 5.
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Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice.I型干扰素受体缺陷可减轻NZB小鼠的狼疮样疾病。
J Exp Med. 2003 Mar 17;197(6):777-88. doi: 10.1084/jem.20021996.
6
Interferon induces pulmonary cysts in A2G mice.干扰素可诱导A2G小鼠出现肺囊肿。
Proc Natl Acad Sci U S A. 1984 Dec;81(24):7937-40. doi: 10.1073/pnas.81.24.7937.
7
Renal deposition of alpha interferon in systemic lupus erythematosus.α干扰素在系统性红斑狼疮中的肾脏沉积。
Infect Immun. 1983 Oct;42(1):368-73. doi: 10.1128/iai.42.1.368-373.1983.
8
Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection.牛分枝杆菌卡介苗处理的小鼠对痘苗病毒感染抵抗力增强的机制
Infect Immun. 1983 Nov;42(2):567-73. doi: 10.1128/iai.42.2.567-573.1983.
9
Glomerular response to immunologic injury, studies on progression.肾小球对免疫损伤的反应：进展性研究
Springer Semin Immunopathol. 1982;5(3):297-320. doi: 10.1007/BF01892090.
10
Interferon as a cause of endoplasmic reticulum abnormalities within hepatocytes in newborn mice.干扰素作为新生小鼠肝细胞内质网异常的一个成因。
Br J Exp Pathol. 1982 Feb;63(1):43-9.
由淋巴细胞性脉络丛脑膜炎病毒急性或持续感染诱导小鼠产生的病毒干扰。
Nature. 1962 Oct 27;196:393-4. doi: 10.1038/196393a0.
4
The biology of lymphocytic choriomeningitis infection: virus-induced immune disease.淋巴细胞性脉络丛脑膜炎感染的生物学：病毒诱导的免疫疾病。
Cold Spring Harb Symp Quant Biol. 1962;27:479-99. doi: 10.1101/sqb.1962.027.001.046.
5
Interference with eastern equine encephalomyelitis (EEE) virus in the brains of mice immune to lymphocytic choriomeningitis (LCM).淋巴细胞性脉络丛脑膜炎（LCM）免疫小鼠脑中对东部马脑脊髓炎（EEE）病毒的干扰
Arch Gesamte Virusforsch. 1961;11:419-27. doi: 10.1007/BF01249595.
6
Observations on immunological tolerance and "immunity" in mice infected congenitally with the virus of lymphocytic choriomeningitis (LCM).关于先天性感染淋巴细胞性脉络丛脑膜炎病毒（LCM）的小鼠的免疫耐受性和“免疫性”的观察
Arch Gesamte Virusforsch. 1960;10:303-4. doi: 10.1007/BF01250677.
7
Lymphocytic choriomeningitis infection of mice as a model for the study of latent virus infection.小鼠淋巴细胞性脉络丛脑膜炎感染作为潜伏病毒感染研究的模型。
Can J Microbiol. 1958 Apr;4(2):149-63. doi: 10.1139/m58-016.
8
Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. II. Relationship of the anti-lymphocytic choriomeningitis immune response to tissue injury in chronic lymphocytic choriomeningitis disease.与持续性淋巴细胞性脉络丛脑膜炎病毒感染相关的慢性疾病的发病机制。II. 慢性淋巴细胞性脉络丛脑膜炎疾病中抗淋巴细胞性脉络丛脑膜炎免疫反应与组织损伤的关系。
J Exp Med. 1970 Jan 1;131(1):1-19. doi: 10.1084/jem.131.1.1.
9
Immunofluorescence study of the mechanism of resistance to superinfection in mice carrying the lymphocytic choriomeningitis virus.携带淋巴细胞性脉络丛脑膜炎病毒的小鼠对重复感染抗性机制的免疫荧光研究
J Pathol Bacteriol. 1966 Apr;91(2):403-15. doi: 10.1002/path.1700910215.
10
Interferon and cell division. VI. Inhibitory effect of interferon on the multiplication of mouse embryo and mouse kidney cells in primary cultures.干扰素与细胞分裂。六、干扰素对原代培养的小鼠胚胎细胞和小鼠肾细胞增殖的抑制作用。
Proc Soc Exp Biol Med. 1971 Dec;138(3):1044-50. doi: 10.3181/00379727-138-36047.