Section on Affective Cognitive Neuroscience, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Building 15K, Room 206, Bethesda, MD, 20892, USA.
Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands.
Neurosci Biobehav Rev. 2018 Aug;91:69-90. doi: 10.1016/j.neubiorev.2016.10.022. Epub 2016 Oct 26.
In this paper, we review fMRI work on neuro-cognitive systems that are considered to be dysfunctional in individuals with conduct problems (i.e., individuals with Conduct Disorder (CD), Oppositional Defiant Disorder (ODD) or antisocial behavior without formal clinical diagnosis). These are: empathy, the acute threat response, reinforcement-based decision-making, response inhibition and the Default Mode Network. Evidence regarding the Default Mode Network is somewhat inconsistent and its functional role/the symptom sets consequent on its dysfunction remain underspecified. However, dysfunctions in the other four neuro-cognitive systems are associated with symptom sets seen in individuals with conduct problems.
在本文中，我们回顾了 fMRI 在神经认知系统方面的工作，这些系统被认为在有行为问题的个体中存在功能障碍（即患有品行障碍（CD）、对立违抗性障碍（ODD）或没有正式临床诊断的反社会行为的个体）。这些系统包括：同理心、急性威胁反应、基于强化的决策、反应抑制和默认模式网络。关于默认模式网络的证据有些不一致，其功能作用/随之出现的功能障碍症状仍未明确。然而，其他四个神经认知系统的功能障碍与行为问题个体中出现的症状集有关。
