Memtsa Pinelopi Theopisti, Tolia Maria, Tzitzikas Ioannis, Bizakis Ioannis, Pistevou-Gombaki Kyriaki, Charalambidou Martha, Iliopoulou Chrysoula, Kyrgias George
School of Health Sciences, Faculty of Medicine, Department of Radiation Oncology, AHEPA University Hospital of Thessaloniki, Aristoteleion University of Thessaloniki, Pinelopi Theopisti Memtsa 26 Psarron str, 54 453, Thessaloniki, PC, Greece.
School of Health Sciences, Faculty of Medicine, Department of Radiation Oncology, University Hospital of Larissa, University of Thessaly, Larissa, Greece.
Support Care Cancer. 2017 Mar;25(3):847-853. doi: 10.1007/s00520-016-3471-0. Epub 2016 Oct 31.
Xerostomia after radiation therapy for head and neck (H&N) cancer has serious effects on patients' quality of life. The purpose of this study was to validate the Greek version of the self-reported eight-item xerostomia questionnaire (XQ) in patients treated with radiotherapy for H&N cancer.
The XQ was translated into Greek and administered to 100 XQ patients. An exploratory factor analysis was performed. Reliability measures were calculated. Several types of validity were evaluated. The observer-rated scoring system was also used.
The mean XQ value was 41.92 (SD 22.71). Factor analysis revealed the unidimensional nature of the questionnaire. High reliability measures (ICC, Cronbach's α, Pearson coefficients) were obtained. Patients differed statistically significantly in terms of XQ score, depending on the RTOG/EORTC classification.
The Greek version of XQ is valid and reliable. Its score is well related to observer's findings and it can be used to evaluate the impact of radiation therapy on the subjective feeling of xerostomia.
头颈部（H&N）癌放射治疗后的口干症对患者的生活质量有严重影响。本研究的目的是在接受H&N癌放射治疗的患者中验证自我报告的八项口干症问卷（XQ）的希腊语版本。
将XQ翻译成希腊语并施用于100名XQ患者。进行了探索性因素分析。计算了可靠性指标。评估了几种效度类型。还使用了观察者评分系统。
XQ的平均得分为41.92（标准差22.71）。因素分析揭示了问卷的单维性质。获得了高可靠性指标（组内相关系数、克朗巴哈α系数、皮尔逊系数）。根据RTOG/EORTC分类，患者在XQ评分方面存在统计学显著差异。
XQ的希腊语版本有效且可靠。其得分与观察者的结果密切相关，可用于评估放射治疗对口干主观感受的影响。
