美国国立综合癌症网络（NCCN）指南、其他指南及生物标志物在结直肠癌筛查中的应用
Use of NCCN Guidelines, Other Guidelines, and Biomarkers for Colorectal Cancer Screening.
作者信息
Williams Christina D, Grady William M, Zullig Leah L
机构信息
From Cooperative Studies Program Epidemiology Center-Durham, Durham VA Medical Center, and Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina; Clinical Research Division, Fred Hutchison Cancer Research Center, and Department of Medicine, University of Washington, Seattle, Washington; and Center for Health Services Research in Primary Care, Durham VA Medical Center, and Division of General Internal Medicine, Duke University Medical Center, Durham, North Carolina.
出版信息
J Natl Compr Canc Netw. 2016 Nov;14(11):1479-1485. doi: 10.6004/jnccn.2016.0154.
Abstract
Colorectal cancer (CRC) remains a common cancer and significant public health burden. CRC-related mortality is declining, partly due to the early detection of CRC through robust screening. NCCN has established the NCCN Guidelines for CRC Screening to help healthcare providers make appropriate screening recommendations according to the patient's risk of developing CRC. This review describes the evolution of CRC screening guidelines for average-risk individuals, discusses the role of NCCN Guidelines for CRC Screening in cancer prevention, and comments on the current and emerging use of biomarkers for CRC screening.
摘要
结直肠癌（CRC）仍然是一种常见癌症，也是重大的公共卫生负担。与CRC相关的死亡率正在下降，部分原因是通过强有力的筛查实现了CRC的早期检测。美国国立综合癌症网络（NCCN）制定了《NCCN结直肠癌筛查指南》，以帮助医疗服务提供者根据患者患CRC的风险做出适当的筛查建议。本综述描述了平均风险个体CRC筛查指南的演变，讨论了《NCCN结直肠癌筛查指南》在癌症预防中的作用，并对目前及新兴的CRC筛查生物标志物的应用进行了评论。
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