Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin 4, Ireland; email:
UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland.
Annu Rev Anim Biosci. 2017 Feb 8;5:329-351. doi: 10.1146/annurev-animal-022516-022747. Epub 2016 Oct 28.
During the last decade, ancient DNA research has been revolutionized by the availability of increasingly powerful DNA sequencing and ancillary genomics technologies, giving rise to the new field of paleogenomics. In this review, we show how our understanding of the genetic basis of animal domestication and the origins and dispersal of livestock and companion animals during the Upper Paleolithic and Neolithic periods is being rapidly transformed through new scientific knowledge generated with paleogenomic methods. These techniques have been particularly informative in revealing high-resolution patterns of artificial and natural selection and evidence for significant admixture between early domestic animal populations and their wild congeners.
在过去的十年中，随着越来越强大的 DNA 测序和辅助基因组学技术的出现，古 DNA 研究发生了革命性的变化，产生了古基因组学这一新领域。在这篇综述中，我们展示了通过使用古基因组学方法产生的新科学知识，我们对动物驯化的遗传基础以及在上旧石器时代和新石器时代期间家畜和伴侣动物的起源和扩散的理解是如何迅速转变的。这些技术在揭示人工和自然选择的高分辨率模式以及早期家畜种群与其野生同系物之间存在大量混合的证据方面特别有启发性。
