Arezzo Alberto, Bini Roberto, Lo Secco Giacomo, Verra Mauro, Passera Roberto
Department of Surgical Sciences, University of Torino, Corso Dogliotti 14, 10126, Turin, Italy.
Department of Surgical Sciences, San Giovanni Bosco Hospital, Turin, Italy.
Surg Endosc. 2017 Jul;31(7):2720-2730. doi: 10.1007/s00464-016-5315-x. Epub 2016 Nov 4.
Complications in colorectal surgery include a wide range of clinical conditions, which increase mortality, morbidity, hospital stay and costs. In some cases, the placement of a self-expanding metal stent may represent a possible therapeutic strategy, avoiding further surgery.
In order to verify the feasibility and safety of the technique, we reviewed the medical literature, between January 1997 and 2015, selecting 32 studies. Inclusion criteria were based on Preferred Reporting Items for Systematic reviews and Meta-Analyses recommendations.
The estimated rate of early success was 73.3% (95% CI 66.3-79.3), raising from 25 to 68% in the time frame 1997-2007. The rate of early complications was 31.4% (95% CI 25.3-38.3%), progressively decreasing from 75 to 43% up to 2009. The rate of surgery for acute complication was 9.3% (95% CI 6.0-14.2%), reduced on time course from 25 to 9%. The rate of closure of dehiscence was 74.5% (95% CI 62.8-83.5%), while the rate of long-lasting success was 57.3% (95% CI 50.3-64.0%).
Endoscopic stenting in the early postoperative management of anastomotic complications after colorectal surgery should be considered in patients with minimal risk for sepsis, as a safe and often effective alternative to surgery. However, in order to establish the safety and efficacy of this technique, prospective studies involving a larger cohort of patients are required.
结直肠手术的并发症包括一系列临床情况,这些情况会增加死亡率、发病率、住院时间和费用。在某些情况下,放置自膨式金属支架可能是一种可行的治疗策略,可避免进一步手术。
为了验证该技术的可行性和安全性,我们回顾了1997年1月至2015年期间的医学文献,筛选出32项研究。纳入标准基于系统评价和Meta分析的首选报告项目建议。
早期成功率估计为73.3%(95%可信区间66.3-79.3),在1997-2007年期间从25%提高到68%。早期并发症发生率为31.4%(95%可信区间25.3-38.3%),到2009年逐渐从75%降至43%。急性并发症的手术率为9.3%(95%可信区间6.0-14.2%),随时间从25%降至9%。裂开闭合率为74.5%(95%可信区间62.8-83.5%),而长期成功率为57.3%(95%可信区间50.3-64.0%)。
对于败血症风险最小的患者,结直肠手术后吻合口并发症的早期术后管理中,内镜支架置入术应被视为一种安全且通常有效的手术替代方法。然而,为了确定该技术的安全性和有效性,需要开展涉及更大患者队列的前瞻性研究。