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下颌阻生第三磨牙手术拔除后经咬肌内注射地塞米松对术后后遗症影响的可能性:一项前瞻性研究

Eventuality of Dexamethasone Injected Intra-massetrically on Post Operative Sequel Following the Surgical Extraction of Impacted Mandibular Third Molars: A Prospective Study.

作者信息

Nandini G D

机构信息

Department of Oral and Maxillofacial Surgery, Sathyabama University Dental College and Hospital, OMR Road, Chennai, 600119 India.

出版信息

J Maxillofac Oral Surg. 2016 Dec;15(4):456-460. doi: 10.1007/s12663-015-0847-5. Epub 2015 Oct 28.

DOI:10.1007/s12663-015-0847-5
PMID:27833337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5083682/
Abstract

OBJECTIVE

The objective of the study was to compare the efficacy of dexamethasone given intra-massetrically via intra buccal approach on postoperative sequele after surgical extraction of impacted mandibular third molars.

METHODOLOGY

Twenty patients, each of who required surgical extraction of a single impacted mandibular third molar under local anesthesia, were randomly set apart to one of the two groups of ten each. The experimental group received dexamethasone 8 mg injected to the masseter muscle intra buccally and the control group did not receive any steroid. Facial swelling and maximal inter-incisal distance were measured by an independent examiner preoperatively, and at 4th h, on the day of surgery, 2 and 7 postoperative days. Pain was measured from the patient's response to a visual analogue scale.

RESULTS

Patients were of the age range 18-40 years. Dexamethasone group showed significant reduction in swelling and pain compared with the control group at all intervals. Dexamethasone injected into the masseter muscle via intra buccal approach resulted in significantly less trismus than control on day one postoperatively.

CONCLUSION

Dexamethasone 8 mg given intra-massetrically through intra buccal approach is an effective way of minimizing swelling, trismus, and pain following surgical extraction of impacted mandibular third molars. It offers a simple, safe, painless, non-invasive and cost-effective treatment.

摘要

目的

本研究的目的是比较经颊侧入路在下颌阻生第三磨牙手术拔除后,通过咬肌内注射地塞米松对术后后遗症的疗效。

方法

20例患者,每例均需在局部麻醉下手术拔除一颗下颌阻生第三磨牙,随机分为两组,每组10例。实验组经颊侧在下颌咬肌内注射8毫克地塞米松,对照组不接受任何类固醇药物。术前、手术当天第4小时、术后第2天和第7天,由一名独立检查者测量面部肿胀和最大切牙间距离。通过患者对视觉模拟量表的反应来测量疼痛程度。

结果

患者年龄在18至40岁之间。在所有时间段内,地塞米松组的肿胀和疼痛程度均明显低于对照组。术后第一天,经颊侧在下颌咬肌内注射地塞米松导致的牙关紧闭程度明显低于对照组。

结论

经颊侧入路在下颌咬肌内注射8毫克地塞米松,是一种有效减轻下颌阻生第三磨牙手术拔除后肿胀、牙关紧闭和疼痛的方法。它提供了一种简单、安全、无痛、非侵入性且经济高效的治疗方法。

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本文引用的文献

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Effect of submucosal and intramuscular dexamethasone on postoperative sequelae after third molar surgery: comparative study.黏膜下和肌内注射地塞米松对第三磨牙手术后后遗症的影响:一项对比研究。
Br J Oral Maxillofac Surg. 2011 Dec;49(8):647-52. doi: 10.1016/j.bjoms.2010.09.021. Epub 2010 Oct 29.
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Corticosteroids reduce postoperative morbidity after third molar surgery: a systematic review and meta-analysis.皮质类固醇可降低第三磨牙手术后的发病率:一项系统评价和荟萃分析。
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