Padial-Molina Miguel, López-Martínez Jesús, O'Valle Francisco, Galindo-Moreno Pablo
Department of Oral Surgery and Implant Dentistry, School of Dentistry, University of Granada Spain.
Department of Pathology and Biopathology and Medicine Regenerative Institute (IBIMER, CIBM), University of Granada Spain.
J Oral Maxillofac Res. 2016 Sep 9;7(3):e10. doi: 10.5037/jomr.2016.7310. eCollection 2016 Jul-Sep.
To describe the microbial profiles of peri-implant diseases and the main detection methods.
A literature search was performed in MEDLINE via PubMed database to identify studies on microbial composition of peri-implant surfaces in humans published in the last 5 years. Studies had to have clear implant status definition for health, peri-implant mucositis and/or peri-implantitis and specifically study microbial composition of the peri-implant sulcus.
A total of 194 studies were screened and 47 included. Peri-implant sites are reported to be different microbial ecosystems compared to periodontal sites. However, differences between periodontal and peri-implant health and disease are not consistent across all studies, possibly due to the bias introduced by the microbial detection technique. New methods non species-oriented are being used to find 'unexpected' microbiota not previously described in these scenarios.
Microbial profile of peri-implant diseases usually includes classic periodontopathogens. However, correlation between studies is difficult, particularly because of the use of different detection methods. New metagenomic techniques should be promoted for future studies to avoid detection bias.
描述种植体周围疾病的微生物特征及主要检测方法。
通过PubMed数据库在MEDLINE中进行文献检索，以识别过去5年发表的关于人类种植体周围表面微生物组成的研究。研究必须对健康、种植体周围黏膜炎和/或种植体周围炎有明确的种植体状态定义，并专门研究种植体周围龈沟的微生物组成。
共筛选出194项研究，纳入47项。据报道，与牙周部位相比，种植体周围部位是不同的微生物生态系统。然而，牙周与种植体周围健康及疾病之间的差异在所有研究中并不一致，这可能是由于微生物检测技术引入的偏差所致。新的非物种定向方法正被用于发现这些情况下以前未描述过的“意外”微生物群。
种植体周围疾病的微生物特征通常包括经典的牙周病原体。然而，各研究之间的相关性很难确定，尤其是因为使用了不同的检测方法。应推广新的宏基因组技术用于未来研究，以避免检测偏差。
