Tan Sock Yin, Praveena Sarva Mangala, Abidin Emilia Zainal, Cheema Manraj Singh
Rev Environ Health. 2016 Dec 1;31(4):447-456. doi: 10.1515/reveh-2016-0026.
Indoor dust acts as a media for heavy metal deposition. Past studies have shown that heavy metal concentration in indoor dust is affected by local human activities and atmospheric transport can have harmful effects on human health. Additionally, children are more sensitive to heavy metals due to their hand-to-mouth behaviour and rapid body development. However, limited information on health risks were found in past dust studies as these studies aimed to identify heavy metal concentrations and sources of indoor dust. The objective of this review is to discuss heavy metal concentration and sources influencing its concentration in indoor dust. Accordingly, high lead (Pb) concentration (639.10 μg/g) has been reported in heavy traffic areas. In addition, this review paper aims to estimate the health risk to children from heavy metals in indoor dust via multiple exposure pathways using the health-risk assessment (HRA). Urban areas and industrial sites have revealed high heavy metal concentration in comparison to rural areas. Hazard index (HI) values found in arsenic (As), chromium (Cr) and Pb were 21.30, 1.10 and 2.40, respectively, indicate that non-carcinogenic elements are found in children. Furthermore, most of the past studies have found that carcinogenic risks for As, cadmium (Cd), Cr and Pb were below the acceptable total lifetime cancer risk (TLCR) range (1×10-6-1×10-4). The results of health risk assessment in this review show that carcinogenic risk exists among children. Hence, this proves that future studies need to focus on children's carcinogenic risk in indoor dust studies in order to find out the sources of heavy metals in indoor dust. This review highlights the importance of having the HRA application using bioavailable heavy metal concentration as it provides more accurate health-risk estimation. Moreover, this review is also useful as a reference for policy decision making in protecting children's health.
室内灰尘是重金属沉积的媒介。过去的研究表明,室内灰尘中的重金属浓度受当地人类活动影响,大气传输可能对人体健康产生有害影响。此外,儿童由于手口行为和身体快速发育,对重金属更为敏感。然而,过去的灰尘研究中关于健康风险的信息有限,因为这些研究旨在确定室内灰尘中重金属的浓度和来源。本综述的目的是讨论影响室内灰尘中重金属浓度的重金属浓度及其来源。因此,在交通繁忙地区已报告有高铅(Pb)浓度(639.10μg/g)。此外,本综述论文旨在通过使用健康风险评估(HRA),通过多种暴露途径估计室内灰尘中重金属对儿童的健康风险。与农村地区相比,城市地区和工业场所的重金属浓度较高。砷(As)、铬(Cr)和Pb的危害指数(HI)值分别为21.30、1.10和2.40,表明在儿童中发现了非致癌元素。此外,过去的大多数研究发现,As、镉(Cd)、Cr和Pb的致癌风险低于可接受的终生总癌症风险(TLCR)范围(1×10-6-1×10-4)。本综述中的健康风险评估结果表明儿童中存在致癌风险。因此,这证明未来的研究需要在室内灰尘研究中关注儿童的致癌风险,以便找出室内灰尘中重金属的来源。本综述强调了使用生物可利用重金属浓度进行HRA应用的重要性,因为它能提供更准确的健康风险估计。此外,本综述也可作为保护儿童健康政策决策的参考。