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2005 - 2012年美国65岁以下患者的心脏应激测试趋势

Cardiac Stress Test Trends Among US Patients Younger Than 65 Years, 2005-2012.

作者信息

Kini Vinay, McCarthy Fenton H, Dayoub Elias, Bradley Steven M, Masoudi Frederick A, Ho P Michael, Groeneveld Peter W

机构信息

Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia2The Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia.

The Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia3Division of Cardiac Surgery, Hospital of the University of Pennsylvania, Philadelphia.

出版信息

JAMA Cardiol. 2016 Dec 1;1(9):1038-1042. doi: 10.1001/jamacardio.2016.3153.

Abstract

IMPORTANCE

After a period of rapid growth, use of cardiac stress testing has recently decreased among Medicare beneficiaries and in a large integrated health system. However, it is not known whether declines in cardiac stress testing are universal or are confined to certain populations.

OBJECTIVE

To determine trends in rates of cardiac stress testing among a large and diverse cohort of commercially insured patients.

DESIGN, SETTING, AND PARTICIPANTS: A serial cross-sectional study with time trends was conducted using administrative claims from all members aged 25 to 64 years belonging to a large, national managed care company from January 1, 2005, to December 31, 2012. Linear trends in rates were determined using negative binomial regression models with procedure count as the dependent variable, calendar quarter as the key independent variable, and the size of the population as a logged offset term. Data analysis was performed from January 1, 2005, to December 31, 2012.

MAIN OUTCOMES AND MEASURES

Age- and sex-adjusted rates of cardiac stress tests per calendar quarter (reported as number of tests per 100 000 person-years).

RESULTS

A total of 2 085 591 cardiac stress tests were performed among 32 921 838 persons (mean [SD] age, 43.2 [10.9] years; 16 625 528 women [50.5%] and 16 296 310 [49.5%] men; 7 604 945 nonwhite [23.1%]). There was a 3.0% increase in rates of cardiac stress testing from 2005 (3486 tests; 95% CI, 3458-3514) to 2012 (3589 tests; 95% CI, 3559-3619; P = .01 for linear trend). Use of nuclear single-photon emission computed tomography decreased by 14.9% from 2005 (1907 tests; 95% CI, 1888-1926) to 2012 (1623 tests; 95% CI, 1603-1643; P = .03). Use of stress echocardiography increased by 27.8% from 2005 (709 tests; 95% CI, 697-721) to 2012 (906 tests; 95% CI, 894 to 920; P < .001). Use of exercise electrocardiography increased by 12.5% from 2005 (861 tests; 95% CI, 847-873) to 2012 (969 tests; 95% CI, 953-985; P < .001). Use of other stress testing modalities increased 65.5% from 2006 (55 tests; 95% CI, 51-59) to 2012 (91 tests; 95% CI, 87-95; P < .001). For individuals aged 25 to 34 years, rates of cardiac stress testing increased 59.1% from 2005 (543 tests; 95% CI, 532-554) to 2012 (864 tests; 95% CI, 852-876; P < .001). For individuals aged 55 to 64 years, rates of cardiac stress testing decreased by 12.3% from 2005 (7894 tests; 95% CI, 7820-7968) to 2012 (6923 tests; 95% CI, 6853-6993; P < .001).

CONCLUSIONS AND RELEVANCE

In contrast to declines in the use of cardiac stress testing in some health care systems, we observed a small increase in its use among a nationally representative cohort of commercially insured patients. Our findings suggest that observed trends in the use of cardiac stress testing may have been driven more by unique characteristics of populations and health systems than national efforts to reduce the overuse of testing.

摘要

重要性

在经历一段快速增长期后,近期医疗保险受益人和一个大型综合医疗系统中心脏应激试验的使用有所减少。然而,尚不清楚心脏应激试验的下降是普遍现象还是仅限于特定人群。

目的

确定一大群不同商业保险患者中心脏应激试验率的趋势。

设计、设置和参与者:采用时间趋势的系列横断面研究,使用了2005年1月1日至2012年12月31日期间一家大型全国性管理式医疗公司中所有年龄在25至64岁成员的管理式医疗索赔数据。使用负二项回归模型确定率的线性趋势,将检查次数作为因变量,日历季度作为关键自变量,人群规模作为对数偏移项。数据分析于2005年1月1日至2012年12月31日进行。

主要结局和测量指标

按日历季度调整年龄和性别的心脏应激试验率(报告为每100 000人年的检查次数)。

结果

在32921838人中总共进行了2085591次心脏应激试验(平均[标准差]年龄,43.2[10.9]岁;女性16625528人[50.5%],男性16296310人[49.5%];非白人7604945人[23.1%])。从2005年(3486次检查;95%CI,3458 - 3514)到2012年(3589次检查;95%CI,3559 - 3619;线性趋势P = 0.01),心脏应激试验率增加了3.0%。2005年(1907次检查;95%CI,1888 - 1926)到2012年(1623次检查;95%CI,1603 - 1643;P = 0.03),核单光子发射计算机断层扫描的使用减少了14.9%。从2005年(709次检查;95%CI,697 - 721)到2012年(906次检查;95%CI,894至920;P < 0.001),负荷超声心动图的使用增加了27.8%。从2005年(861次检查;95%CI,847 - 873)到2012年(969次检查;95%CI,953 - 985;P < 0.001),运动心电图的使用增加了12.5%。从2006年(55次检查;95%CI,51 - 59)到2012年(91次检查;95%CI,87 - 95;P < 0.001),其他应激试验方式的使用增加了65.5%。对于25至34岁的个体,心脏应激试验率从2005年(543次检查;95%CI,532 - 554)到2012年(864次检查;95%CI,852 - 876;P < 0.001)增加了59.1%。对于55至64岁的个体,心脏应激试验率从2005年(7894次检查;95%CI,7820 - 7968)到2012年(6923次检查;95%CI,6853 - 6993;P < 0.001)下降了12.3%。

结论与意义

与一些医疗系统中心脏应激试验使用的下降情况相反,我们观察到在全国具有代表性的商业保险患者队列中其使用略有增加。我们的研究结果表明,观察到的心脏应激试验使用趋势可能更多地是由人群和医疗系统的独特特征驱动,而非全国性减少过度检查的努力。

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