de Sá Cavalcanti Felipe Lira, Mendes-Marques Carina Lucena, Vasconcelos Crhisllane Rafaele Dos Santos, de Lima Campos Túlio, Rezende Antonio Mauro, Xavier Danilo Elias, Leal Nilma Cintra, de-Melo-Neto Osvaldo Pompilio, de Morais Marcia Maria Camargo, Leal-Balbino Tereza Cristina
Laboratório de Resistência Microbiana, Instituto de Ciências Biológicas, Universidade de Pernambuco, Recife, Brazil.
Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.
Antimicrob Agents Chemother. 2016 Dec 27;61(1). doi: 10.1128/AAC.01309-16. Print 2017 Jan.
Here, we report the isolation of 31 Acinetobacter baumannii strains producing OXA-253 in a single large Brazilian city. These strains belonged to five different sequence types (STs), including 4 STs not previously associated with bla In all strains, the bla gene was located in a plasmid within a genetic environment similar to what was found previously in Brazil and Italy. The reported data emphasize the successful transmission of the bla gene through a large area and the tendency for this resistance determinant to remain in the A. baumannii population.
在此，我们报告在巴西一个大城市中分离出31株产OXA-253的鲍曼不动杆菌菌株。这些菌株属于五种不同的序列类型（STs），包括4种先前未与bla相关的STs。在所有菌株中，bla基因位于一个质粒中，其遗传环境与先前在巴西和意大利发现的相似。报告的数据强调了bla基因在大面积区域的成功传播以及这种耐药决定因素在鲍曼不动杆菌群体中持续存在的趋势。
