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老年女性患者结肠镜检查中超薄器械与儿科器械的比较:一项随机试验。

Ultrathin versus pediatric instruments for colonoscopy in older female patients: A randomized trial.

作者信息

Nemoto Daiki, Utano Kenichi, Endo Shungo, Isohata Noriyuki, Hewett David G, Togashi Kazutomo

机构信息

Department of Coloproctology, Aizu Medical Center, Fukushima Medical University, Aizuwakamatsu-City, Japan.

University of Queensland, School of Medicine, Brisbane, Australia.

出版信息

Dig Endosc. 2017 Mar;29(2):168-174. doi: 10.1111/den.12761. Epub 2016 Dec 2.

Abstract

BACKGROUND AND AIM

Small-caliber endoscopes such as gastroscopes or pediatric colonoscopes are occasionally required to negotiate fixed or angulated colons. However, the use of a new ultrathin instrument (diameter 7.0 mm) narrower than other conventional colonoscopes has not been evaluated. The aim of the present study was to compare the use compare the use of an ultrathin colonoscope (UTC) with a pediatric colonoscope (PDC) for colonoscopy in older female patients.

METHODS

A prospective, randomized, controlled trial was conducted in a single academic endoscopy unit. A total of 77 female patients aged ≥70 years undergoing unsedated colonoscopy were randomized to colonoscopy with a UTC (n = 39) or PDC (n = 38). Primary outcome measurement was the degree of pain using a numerical rating scale, and secondary outcomes were cecal intubation rate, ileal intubation rate, time to cecum and adenoma detection rate.

RESULTS

There was a significant difference in reported pain using the numerical rating scale (median, UTC 1 vs PDC 4, P < 0.0001). Cecal intubation rates were 97.4% in UTC and 92.1% in PDC (P = 0.36), and ileal intubation rates were 82.0% and 89.4% (P = 0.76), respectively. However, median times to cecum were significantly longer using UTC compared with PDC (15.2 min vs 11.1 min, P = 0.022). Adenoma detection rates were 30.7% in UTC and 26.3% in PDC (P = 0.80).

CONCLUSIONS

Colonoscopy using UTC was almost equivalent to that of PDC in older female patients, with significantly less pain compared with PDC. UTC may be an alternative to PDC for the difficult colon.

摘要

背景与目的

诸如胃镜或小儿结肠镜等小口径内窥镜偶尔需要用于通过固定或成角的结肠。然而,一种比其他传统结肠镜更窄的新型超薄器械(直径7.0毫米)的使用尚未得到评估。本研究的目的是比较在老年女性患者中使用超薄结肠镜(UTC)和小儿结肠镜(PDC)进行结肠镜检查的情况。

方法

在一个学术性内镜检查单位进行了一项前瞻性、随机、对照试验。共有77名年龄≥70岁且未接受镇静的女性患者被随机分配接受UTC结肠镜检查(n = 39)或PDC结肠镜检查(n = 38)。主要结局指标是使用数字评分量表评估的疼痛程度,次要结局指标是盲肠插管率、回肠插管率、到达盲肠的时间和腺瘤检出率。

结果

使用数字评分量表报告的疼痛程度存在显著差异(中位数,UTC为1,PDC为4,P < 0.0001)。UTC的盲肠插管率为97.4%,PDC为92.1%(P = 0.36),回肠插管率分别为82.0%和89.4%(P = 0.76)。然而,与PDC相比,使用UTC到达盲肠的中位时间显著更长(15.2分钟对11.1分钟,P = 0.022)。UTC的腺瘤检出率为30.7%,PDC为26.3%(P = 0.80)。

结论

在老年女性患者中,使用UTC进行结肠镜检查与使用PDC几乎相当,且与PDC相比疼痛明显减轻。对于困难的结肠检查,UTC可能是PDC的一种替代方法。

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