Department of Gastroenterology, Mizonokuchi Hospital, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki, Kanagawa, 213-8507, Japan.
Division of Gastroenterology, Department of Internal Medicine, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-ku, Tokyo, 153-8515, Japan.
Surg Endosc. 2017 Dec;31(12):5150-5158. doi: 10.1007/s00464-017-5581-2. Epub 2017 May 9.
Ultrathin colonoscopes (UTC) reportedly produce less pain during colonoscopy than standard colonoscopes. The aim of this study was to assess the tolerability of an UTC compared with that of a pediatric colonoscope.
A total of 270 adult patients scheduled to undergo colonoscopy were randomized, with 134 allocated to the UTC group and 136 to the pediatric colonoscope group. Pain was assessed using a visual analog scale. For all procedures, sedation was administered only if requested. Overall pain, rate and time of cecal and terminal ileum intubation, number of patients requesting sedation, adenoma detection rates (ADR), and rate of complications were measured and analyzed.
Among all patients, the medians of maximum pain and overall pain were significantly lower in the UTC group than in the pediatric colonoscope group (23 vs. 38, P < 0.001; 12 vs. 22, P = 0.0003, respectively). Significantly fewer patients requested sedation in the UTC group than in the pediatric colonoscope group (1.4 vs. 6.6%; P = 0.0269). No significant differences were seen in either the rate and time of successful cecal and terminal ileum intubation, or in other procedure-related outcomes, including ADR.
Compared with a pediatric colonoscope, the UTC was associated with reduced overall and maximum pain during colonoscopy, with no difference in ADR.
超微结肠镜(UTC)据称在结肠镜检查期间引起的疼痛比标准结肠镜检查少。本研究的目的是评估 UTC 与儿科结肠镜相比的耐受性。
总共 270 名计划接受结肠镜检查的成年患者被随机分组,134 名患者分配到 UTC 组,136 名患者分配到儿科结肠镜组。使用视觉模拟量表评估疼痛。所有程序仅在要求时给予镇静。测量和分析所有程序的总体疼痛、疼痛发生率和时间、要求镇静的患者人数、腺瘤检出率(ADR)和并发症发生率。
在所有患者中,UTC 组的最大疼痛和总体疼痛中位数明显低于儿科结肠镜组(23 对 38,P < 0.001;12 对 22,P = 0.0003)。UTC 组要求镇静的患者明显少于儿科结肠镜组(1.4%对 6.6%;P = 0.0269)。在成功插管回盲部和末端回肠的发生率和时间方面,或在其他与程序相关的结果方面,包括 ADR,均未见显著差异。
与儿科结肠镜相比,UTC 与结肠镜检查期间的总体和最大疼痛减轻相关,ADR 无差异。