Corneal Aberrations, Contrast Sensitivity, and Light Distortion in Orthokeratology Patients: 1-Year Results.

To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = -2.19 ± 0.97 D were evaluated at 1 day, 1 month, and 1 year after starting OK treatment. Monocular LD, photopic monocular CSF, and corneal HOA for 6 mm pupil size were measured. LD showed an increase after the first night ( < 0.05) and recovery to baseline after 1 month, remaining stable after 1 year ( > 0.05). Spherical-like, coma-like, and secondary astigmatism HOA RMS increased significantly ( ≤ 0.022) from baseline to 1-month visit, remaining unchanged over the follow-up. Contrast sensitivity for medium frequencies (3.0, 4.24, and 6.00 cpd) was significantly correlated with LD parameters at baseline ( ≤ -0.529, < 0.001). However, after 1 year of treatment, this correlation was only statistically significant for 12 cpd spatial frequency ( ≤ -0.565, < 0.001). Spherical-like RMS for 6 mm pupil size correlated with irregularity of the LD ( = -0.420, < 0.05) at the 1-year visit. LD experienced by OK patients recovers after one month of treatment and remains stable in the long term while optical aberrations remain significantly higher than baseline.