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袖状胃切除术和Roux-en-Y胃旁路术后胃肠道生活质量显著改善——一项为期2年随访的前瞻性横断面研究

Gastrointestinal Quality of Life Improves Significantly After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass-a Prospective Cross-Sectional Study Within a 2-Year Follow-up.

作者信息

Nickel Felix, Schmidt Lukas, Bruckner Thomas, Billeter Adrian T, Kenngott Hannes G, Müller-Stich Beat-Peter, Fischer Lars

机构信息

Department of General, Visceral, and Transplant Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

Institute for Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 305, 69120, Heidelberg, Germany.

出版信息

Obes Surg. 2017 May;27(5):1292-1297. doi: 10.1007/s11695-016-2464-x.

Abstract

INTRODUCTION

Morbidly obese patients have lower quality of life (QOL) when compared to the general population. So far, no studies have compared gender and procedural differences in gastrointestinal QOL after sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB).

METHODS

Patients before and after bariatric surgery completed the gastrointestinal quality of life index (GIQLI), a 36-item questionnaire with five subscores. Differences between SG and RYGB were analyzed, as were gender differences.

RESULTS

Some 186 patients completed the questionnaire, 75 before surgery, 56 within 6 months, and 55 within 24 months after surgery. Total GIQLI score and all subscores were significantly better within 24 months after surgery (80.9 ± 19.2 vs. 109.2 ± 17.7, p < 0.001). The specific gastrointestinal items 'feeling of fullness', 'eating pleasure', 'slow speed of eating', and 'diarrhea' were also significantly better after surgery whereas many other gastrointestinal items were not different. Total GIQLI score was significantly higher for SG than for RYGB within 6 months, while there were no significant differences within 24 months after surgery. There were also no significant differences in specific gastrointestinal items between SG and RYGB within 24 months after surgery and in total GIQLI score between female and male patients.

CONCLUSION

Total GIQLI score and all subscores were higher within 24 months after bariatric surgery. Total GIQLI score was significantly higher after SG when compared to RYGB within 6 months, but not different within 24 months after surgery. There was no difference in total GIQLI score between female and male patients.

摘要

引言

与普通人群相比,病态肥胖患者的生活质量(QOL)较低。到目前为止,尚无研究比较袖状胃切除术(SG)和 Roux-en-Y 胃旁路术(RYGB)后胃肠道生活质量的性别差异和手术方式差异。

方法

减肥手术前后的患者完成了胃肠道生活质量指数(GIQLI),这是一份包含 36 个项目且有五个子评分的问卷。分析了 SG 和 RYGB 之间的差异以及性别差异。

结果

约 186 名患者完成了问卷,75 名在手术前,56 名在术后 6 个月内,55 名在术后 24 个月内。术后 24 个月内,GIQLI 总分及所有子评分均显著改善(80.9±19.2 对 109.2±17.7,p<0.001)。术后“饱腹感”“进食愉悦感”“进食速度慢”和“腹泻”等特定胃肠道项目也有显著改善,而许多其他胃肠道项目则无差异。术后 6 个月内,SG 的 GIQLI 总分显著高于 RYGB,而术后 24 个月内无显著差异。术后 24 个月内,SG 和 RYGB 在特定胃肠道项目上以及女性和男性患者在 GIQLI 总分上均无显著差异。

结论

减肥手术后 24 个月内,GIQLI 总分及所有子评分均升高。与 RYGB 相比,SG 术后 6 个月内 GIQLI 总分显著更高,但术后 24 个月内无差异。女性和男性患者的 GIQLI 总分无差异。

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