Kim Sue-Jeong, Lee Young, Seo Young-Joon, Lee Jeung-Hoon, Im Myung
*All authors are affiliated with the Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
Dermatol Surg. 2017 Feb;43(2):204-209. doi: 10.1097/DSS.0000000000000968.
Laser and light-based therapies have been used successfully in the treatment of rosacea; however, evidence is lacking regarding the efficacy of radiofrequency (RF).
This study evaluated the efficacy of RF in the treatment of rosacea compared with pulsed dye laser (PDL).
Thirty patients with rosacea (erythematotelangiectatic rosacea [ETR], n = 20; papulopustular rosacea [PPR], n = 10) were enrolled in a randomized, controlled, split-face study. The patients were treated with RF on one side and PDL on the other side. Each treatment consisted of 3 sessions at 4-week intervals and followed up until 4 weeks after the last treatment. Efficacy was assessed by rosacea severity score, erythema index, lesion counts, physician's subjective evaluation, and patient's satisfaction.
Radiofrequency and PDL resulted in significant improvement in severity scores and erythema and 70% of the patients receiving RF treatment showed a clinical improvement of >50%. No significant difference was noted between RF and PDL treatment in ETR. However, RF treatment led to a significantly greater decrease in papulopustular lesion count and rosacea severity score in PPR compared with PDL treatment.
RF therapy was effective in the treatment of rosacea. It should be considered an alternative therapeutic option, especially in PPR.
激光和光基疗法已成功用于治疗酒渣鼻；然而，关于射频（RF）疗效的证据尚缺。
本研究评估了射频与脉冲染料激光（PDL）相比治疗酒渣鼻的疗效。
30例酒渣鼻患者（红斑毛细血管扩张型酒渣鼻[ETR]，n = 20；丘疹脓疱型酒渣鼻[PPR]，n = 10）纳入一项随机、对照、半脸研究。患者一侧接受射频治疗，另一侧接受脉冲染料激光治疗。每次治疗包括3次，间隔4周，随访至最后一次治疗后4周。通过酒渣鼻严重程度评分、红斑指数、皮损计数、医生主观评估和患者满意度评估疗效。
射频和脉冲染料激光治疗后严重程度评分和红斑均有显著改善，70%接受射频治疗的患者临床改善>50%。在红斑毛细血管扩张型酒渣鼻患者中，射频和脉冲染料激光治疗之间未观察到显著差异。然而，与脉冲染料激光治疗相比，射频治疗导致丘疹脓疱型酒渣鼻患者的丘疹脓疱皮损计数和酒渣鼻严重程度评分显著降低。
射频疗法治疗酒渣鼻有效。应将其视为一种替代治疗选择，尤其是在丘疹脓疱型酒渣鼻患者中。
