Bazzano Alessandra N, Littrell Lisa, Lambert Stephen, Roi Cody
Department of Global Community Health and Behavioral Sciences, Tulane University School of Public Health and Tropical Medicine, Tulane University.
Department of Psychiatry, Louisiana State University Health Sciences Center, Louisiana State University, New Orleans, LA, USA.
Neuropsychiatr Dis Treat. 2016 Nov 15;12:2973-2980. doi: 10.2147/NDT.S122979. eCollection 2016.
Recent evidence has indicated a potential role of vitamin D3 in a range of neuropsychiatric outcomes, as well as on cognitive function, but conflicting data have left that role uncertain. Understanding potential associations of vitamin D status with psychiatric illness will allow clinicians to better assess therapeutic options. Few studies have examined vitamin D status among a racially diverse group of psychiatric patients who have been hospitalized, and none has done so in the southern US where socioeconomic inequality is high.
In this retrospective study, medical records from 113 patients hospitalized for psychiatric illness were retrieved and analyzed. Vitamin D status in this population was estimated, along with any patterns of association between deficiency and risk factors.
The vast majority of patients hospitalized for psychiatric illness in this biracial, low-income sample had either insufficient or deficient vitamin D levels. African-American patients had lower levels of vitamin D than Caucasian patients.
Our findings demonstrate that hospitalized psychiatric patients are at increased risk for vitamin D deficiency and in particular low-income, African-American populations. These results suggest that vitamin D should be assessed and therapy considered at the initiation of psychiatric hospitalizations.
最近的证据表明维生素D3在一系列神经精神疾病结局以及认知功能方面具有潜在作用，但相互矛盾的数据使得该作用尚不确定。了解维生素D状态与精神疾病之间的潜在关联将有助于临床医生更好地评估治疗方案。很少有研究在种族多样的住院精神科患者群体中检测维生素D状态，而在美国社会经济不平等程度较高的南部地区则尚无此类研究。
在这项回顾性研究中，检索并分析了113名因精神疾病住院患者的病历。评估了该人群的维生素D状态以及维生素D缺乏与风险因素之间的任何关联模式。
在这个双种族、低收入样本中，绝大多数因精神疾病住院的患者维生素D水平不足或缺乏。非裔美国患者的维生素D水平低于白种人患者。
我们的研究结果表明，住院精神科患者维生素D缺乏风险增加，尤其是低收入非裔美国人群。这些结果表明，在精神科住院治疗开始时应评估维生素D水平并考虑进行治疗。
