Zakharov V V, Mamedov L A, Meshcheriakova S A, Shekhter A B, Kapitonov N I
Biull Eksp Biol Med. 1989 Jun;107(6):690-3.
On 220 male Wistar rats with models of aseptic and contaminated skin wounds the authors studied interrelationship between serotonin and hydroperoxide in the wound tissues and the blood. A comparative analysis of the changes of these indices in the blood and tissues showed that the degree of these disorders on the 1st day after the operation was determined by operational trauma and with the development of purulent inflammation intensive initiation of lipoperoxidation products takes place.
在220只建立了无菌和污染性皮肤伤口模型的雄性Wistar大鼠身上,作者研究了伤口组织和血液中血清素与过氧化氢之间的相互关系。对血液和组织中这些指标变化的比较分析表明,术后第1天这些紊乱的程度由手术创伤决定,并且随着化脓性炎症的发展,脂质过氧化产物大量产生。