含胺氟化物/氟化亚锡的牙膏和漱口水对牙菌斑、牙龈炎、菌斑及牙釉质氟蓄积的影响。
Effect of amine fluoride/stannous fluoride-containing toothpaste and mouthrinsings on dental plaque, gingivitis, plaque and enamel F-accumulation.
作者信息
Bánóczy J, Szöke J, Kertész P, Töth Z, Zimmermann P, Gintner Z
机构信息
Department of Conservative Dentistry, Faculty of Dentistry, Semmelweis Medical University, Budapest, Hungary.
出版信息
Caries Res. 1989;23(4):284-8. doi: 10.1159/000261193.
The aim of the study was to assess the effect of an amine fluoride/stannous fluoride toothpaste and mouthwash on dental plaque and gingivitis, plaque F- accumulation, F- content and acid solubility of dental enamel. Participants in the 12-week double-blind study were 92 schoolchildren, with a mean age of 12.4 years, randomly distributed to four groups: (1) AmF/SnF2 toothpaste, (2) placebo toothpaste, (3) AmF/SnF2 toothpaste plus AmF/SnF2 mouthwash, (4) placebo toothpaste plus AmF/SnF2 mouthwash. Analyzing the results, the mean values of dental plaque (Silness-Löe index) and of the sulcus bleeding index decreased statistically significantly in all groups except the placebo toothpaste users. Plaque F- and enamel F- content increased considerably only in the two groups using the AmF/SnF2 toothpaste. A decrease in acid solubility was significant only in the group of both test toothpaste and test mouthwash users. Thus the clinical efficacy of the tested AmF/SnF2 toothpaste might be increased by the combined use of mouthrinsings containing the same substances.
该研究的目的是评估胺氟化物/氟化亚锡牙膏和漱口水对牙菌斑、牙龈炎、菌斑氟积累、牙釉质氟含量及酸溶解性的影响。这项为期12周的双盲研究的参与者为92名学童，平均年龄12.4岁，随机分为四组：（1）胺氟化物/氟化亚锡牙膏组；（2）安慰剂牙膏组；（3）胺氟化物/氟化亚锡牙膏加胺氟化物/氟化亚锡漱口水组；（4）安慰剂牙膏加胺氟化物/氟化亚锡漱口水组。分析结果显示，除使用安慰剂牙膏的组外，所有组的牙菌斑（Silness-Löe指数）和龈沟出血指数的平均值均有显著统计学下降。仅在使用胺氟化物/氟化亚锡牙膏的两组中，菌斑氟和牙釉质氟含量显著增加。仅在使用测试牙膏和测试漱口水的组中，酸溶解性降低显著。因此，联合使用含有相同物质的漱口水可能会提高测试的胺氟化物/氟化亚锡牙膏的临床疗效。
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