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Lyme Arrhythmia in an Avid Golfer: A Diagnostic Challenge and a Therapeutic Dilemma.一位狂热高尔夫球手的莱姆病心律失常:诊断挑战与治疗困境
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Modulation of atrioventricular conduction by ablation of the "slow" atrioventricular node pathway in patients with drug-refractory atrial fibrillation or flutter.药物难治性心房颤动或心房扑动患者中,通过消融“慢”房室结径路对房室传导进行调制。
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[Modulation of atrioventricular conduction in patients with atrial fibrillation or flutter. Immediate and long-term results].[心房颤动或心房扑动患者房室传导的调制。即时和长期结果]
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Pacing-induced alternate Wenckebach periods: incidence and clinical significance.
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Manifestations of Lyme carditis.莱姆病性心脏病的表现。
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Successful treatment of fulminant Lyme myocarditis with mechanical circulatory support in a young male adult: a case report.一名年轻男性成人暴发性莱姆心肌炎经机械循环支持成功治疗:病例报告
Croat Med J. 2017 Apr 14;58(2):185-193. doi: 10.3325/cmj.2017.58.185.

本文引用的文献

1
Three sudden cardiac deaths associated with Lyme carditis - United States, November 2012-July 2013.三例与莱姆心炎相关的心脏性猝死 - 美国,2012 年 11 月至 2013 年 7 月。
MMWR Morb Mortal Wkly Rep. 2013 Dec 13;62(49):993-6.
2
Atrial fibrillation, complete atrioventricular block and escape rhythm with bundle-branch block morphologies: an exceptional presentation of Lyme carditis.心房颤动、完全性房室传导阻滞及伴有束支传导阻滞形态的逸搏心律:莱姆病性心肌炎的一种特殊表现
Int J Cardiol. 2012 Sep 20;160(1):e12-4. doi: 10.1016/j.ijcard.2012.01.004. Epub 2012 Feb 2.
3
The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America.莱姆病、人粒细胞无形体病和巴贝斯虫病的临床评估、治疗及预防:美国传染病学会临床实践指南
Clin Infect Dis. 2006 Nov 1;43(9):1089-134. doi: 10.1086/508667. Epub 2006 Oct 2.
4
Surveillance for Lyme disease--United States, 1992-1998.美国1992 - 1998年莱姆病监测
MMWR CDC Surveill Summ. 2000 Apr 28;49(3):1-11.
5
Lyme carditis: cardiac abnormalities of Lyme disease.莱姆病性心脏炎:莱姆病的心脏异常表现。
Ann Intern Med. 1980 Jul;93(1):8-16. doi: 10.7326/0003-4819-93-1-8.
6
Surveillance of Lyme disease in the United States, 1982.
J Infect Dis. 1985 Jun;151(6):1144-9. doi: 10.1093/infdis/151.6.1144.
7
Lyme disease.莱姆病
N Engl J Med. 1989 Aug 31;321(9):586-96. doi: 10.1056/NEJM198908313210906.
8
Persistent atrioventricular block in Lyme borreliosis.莱姆病中的持续性房室传导阻滞。
Klin Wochenschr. 1990 Apr 17;68(8):431-5. doi: 10.1007/BF01648587.
9
Lyme carditis: clinical characteristics of 105 cases.莱姆病性心脏炎:105例临床特征
Scand J Infect Dis Suppl. 1991;77:81-4.

一位狂热高尔夫球手的莱姆病心律失常:诊断挑战与治疗困境

Lyme Arrhythmia in an Avid Golfer: A Diagnostic Challenge and a Therapeutic Dilemma.

作者信息

Rastogi Ujjwal, Kumars Nidhi

机构信息

James J. Peter VA Medical Center/The Mount Sinai Hospital.

出版信息

J Atr Fibrillation. 2016 Feb 29;8(5):1378. doi: 10.4022/jafib.1378. eCollection 2016 Feb-Mar.

DOI:10.4022/jafib.1378
PMID:27909484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5089497/
Abstract

Lyme disease is a multisystem disorder affecting dermatologic, cardiac, nervous and musculoskeletal systems. Cardiac manifestations occur in about 5% of Lyme infections and stem from the involvement of the cardiac conduction system, resulting in varying degrees of sino-atrioventricular block. Occasionally, Lyme infection may also present with myopericarditis. Unlike isolated conduction node disease, myocardial involvement presents a great diagnostic and therapeutic dilemma for the physician. We report the case of a 68 year-old male cardiologist who presented with new onset exertional dyspnea and palpitations. Electrocardiograms revealed intermittent Wenckebach with markedly prolonged PR interval varying between 290-350ms. During his hospitalization, he also had a transient episode of atrial fibrillation/flutter with AV block. The patient was promptly treated with intravenous Ceftriaxone. He remained hemodynamically stable, and within 48 hours of antibiotic treatment, the patient's arrhythmias began to resolve, and the PR interval had shortened to 230ms. He was discharged on oral Doxycyline for three weeks.

摘要

莱姆病是一种影响皮肤、心脏、神经和肌肉骨骼系统的多系统疾病。心脏表现约见于5%的莱姆病感染,源于心脏传导系统受累,导致不同程度的窦房房室传导阻滞。偶尔,莱姆病感染也可能表现为心肌心包炎。与孤立的传导节点疾病不同,心肌受累给医生带来了巨大的诊断和治疗难题。我们报告一例68岁男性心脏病专家的病例,他出现新发劳力性呼吸困难和心悸。心电图显示间歇性文氏现象,PR间期明显延长,在290 - 350毫秒之间变化。住院期间,他还出现了伴有房室传导阻滞的短暂房颤/房扑发作。患者立即接受静脉注射头孢曲松治疗。他的血流动力学保持稳定,在抗生素治疗48小时内,患者的心律失常开始缓解,PR间期缩短至230毫秒。他出院时口服多西环素三周。