Graham Barney S, Repik Patricia M, Yactayo Sergio
Vaccine Research Center.
Virology Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
J Infect Dis. 2016 Dec 15;214(suppl 5):S510-S513. doi: 10.1093/infdis/jiw370.
Discovered in 1953, chikungunya virus (CHIKV) circulated in Africa and Southeast Asia, with periodic outbreaks, for many years. Highly efficient transmission following a genetic mutation of the virus in 2005 caused its global spread. Associated with significant morbidity, CHIKV creates a large public health burden, and despite various efforts, there are currently no licensed vaccines nor specific treatments. To garner a better understanding of the virus, identify gaps in knowledge, and guide the development of more-effective interventions, the World Health Organization and National Institute of Allergy and Infectious Diseases assembled global experts for discussion and review. Herein described are the outcomes.
基孔肯雅病毒（CHIKV）于1953年被发现，多年来一直在非洲和东南亚传播，并周期性爆发。2005年该病毒发生基因突变后高效传播，导致其在全球蔓延。CHIKV引发了大量发病情况，造成了巨大的公共卫生负担，尽管做出了各种努力，但目前尚无获批的疫苗，也没有特效治疗方法。为了更好地了解该病毒，找出知识空白，并指导开发更有效的干预措施，世界卫生组织和美国国立过敏与传染病研究所召集了全球专家进行讨论和审议。以下是讨论结果。
