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意大利吸烟、饮用咖啡、可可和茶与膀胱癌死亡率的关系。

Tobacco smoking, coffee, cocoa and tea consumption in relation to mortality from urinary bladder cancer in Italy.

作者信息

Pannelli F, La Rosa F, Saltalamacchia G, Vitali R, Petrinelli A M, Mastrandrea V

机构信息

Dipartimento di Scienze Igienistiche e Sanitarie-Ambientali, University of Camerino, Italy.

出版信息

Eur J Epidemiol. 1989 Sep;5(3):392-7. doi: 10.1007/BF00144843.

Abstract

This paper examines changes in mortality from urinary bladder cancer in Italy during the years 1950-81 in relation to changes in smoking habits and in coffee, cocoa and tea consumption. The authors found that, in both sexes and for all ages, mortality has been increasing throughout this period, although the rates and relative increase have consistently been much lower and more gradual for women than for men. From the analysis of age-cohort-period variation it seems that bladder cancer mortality can also be influenced by changes in smoking habit patterns and by variation in the quality of diagnoses. The increase in death risk for both sexes in Italy up to cohorts born around 1905-10 can be related to occupational exposures and to high-tar-content tobacco smoking, whereas the tendency for mortality rates to stabilize and decline in cohorts born after 1910 were influenced by changes from high-tar-content and no-filter cigarettes to low-tar-content and filter cigarettes and by prevention measures taken in at-risk working environments. The consumption of coffee, cocoa and tea does not seem to be related to the increase in bladder cancer risk in Italy.

摘要

本文研究了1950年至1981年间意大利膀胱癌死亡率的变化,以及吸烟习惯和咖啡、可可及茶消费量的变化。作者发现,在这一时期,无论男女及各年龄段,死亡率均呈上升趋势,不过女性的死亡率及相对增幅一直远低于男性,且更为平缓。通过对年龄-队列-时期变化的分析,似乎膀胱癌死亡率还会受到吸烟习惯模式变化及诊断质量差异的影响。意大利1905年至1910年左右出生的队列之前,男女死亡风险的增加可能与职业暴露及高焦油含量烟草的吸食有关,而1910年之后出生的队列死亡率趋于稳定和下降的趋势,则受到从高焦油含量无过滤嘴香烟向低焦油含量过滤嘴香烟的转变,以及在高危工作环境中采取的预防措施的影响。在意大利,咖啡、可可和茶的消费量似乎与膀胱癌风险的增加无关。

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