Smith M M, Vasseur P B, Saunders H M
Veterinary Medical Teaching Hospital, University of California, Davis 95616.
J Am Vet Med Assoc. 1989 Sep 15;195(6):765-7.
Tissue and swab specimens for bacteriologic culture were obtained from the operative wound in 40 dogs in which plates and screws were applied and then removed from the sites of healed fractures or arthrodeses. Implants were removed after a mean (+/- SD) application period of 15.7 +/- 9.3 months. Bacteria were isolated from the plate-bone interface in 17 dogs. Of the 17 dogs, 9 had had complications associated with initial management (eg, osteomyelitis, open fractures, or multiple surgical procedures). Control specimens were obtained from 30 dogs that had clean elective orthopedic procedures that did not involve implantation of metallic prostheses. None of the dogs of the control group were given antibiotics. Bacteria were isolated from 2 of 30 specimens obtained from control dogs. The difference between the number of culture-positive specimens from dogs of the implant group and those from dogs of the control group was significant (P less than 0.01).
从40只应用钢板和螺钉然后从愈合骨折或关节固定部位取出钢板和螺钉的犬的手术伤口获取组织和拭子标本用于细菌学培养。植入物在平均（±标准差）应用期15.7±9.3个月后取出。17只犬的钢板-骨界面分离出细菌。这17只犬中，9只曾有与初始处理相关的并发症（如骨髓炎、开放性骨折或多次外科手术）。对照标本取自30只接受不涉及金属假体植入的清洁择期骨科手术的犬。对照组的犬均未给予抗生素。从对照犬获取的30份标本中有2份分离出细菌。植入组犬的培养阳性标本数量与对照组犬的培养阳性标本数量之间差异有统计学意义（P<0.01）。
