Antibiotic discovery is a walk in the park.
作者信息
Nothias Louis-Félix, Knight Rob, Dorrestein Pieter C
机构信息
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093.
Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093.
出版信息
Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14477-14479. doi: 10.1073/pnas.1618221114. Epub 2016 Dec 9.
Abstract
摘要
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Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14477-14479. doi: 10.1073/pnas.1618221114. Epub 2016 Dec 9.
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Mycins v Microbes Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues by Martin J. Blaser (2014) Holt New York, USA.《霉菌与微生物 缺失的微生物：抗生素的过度使用如何引发现代瘟疫》 作者：马丁·J·布莱泽（2014年） 美国纽约霍尔特出版社
FASEB J. 2014 Sep;28(9):3821-3822. doi: 10.1096/fj.14-0901ufm.
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