Bioactivity of Methanolic Extracts from (Schltdl.) Schiede ex Standl., L., DC., F. Delaroche, and (Roxb.) Benth. Used in Traditional Medicine in Mexico.

Seven out of eight methanolic extracts from five plants native to Mexico were inactive against ten bacterial strains of clinical interest. The fruit extract of inhibited the bacteria (MIC = 4375 g/ml), (MIC = 1094 g/ml), and (MIC = 137 g/ml). The fruit extract of was with CC = 45 g/ml most cytotoxic against the cell-line Caco-2, followed by the leaf extract from (CC = 126 g/ml); interestingly, leaves of (CC = 563 g/ml) and bark of (CC = 347 g/ml) extracts were much less cytotoxic. We describe for the first time the cytotoxic effect from extracts of the aerial parts and the flowers of (CC = 323 g/ml and CC = 250 g/ml, resp.). Phytochemical analysis demonstrated for both extracts high tannin and saponin and low flavonoid content, while terpenoids were found in the flowers. For the first time we report a cytotoxicological study on an extract of (CC = 356 g/ml) and likewise the bark extract from (CC = 342 g/ml). In conclusion the fruit extract of is a potential candidate for further biological studies.