van der Kamp W, Berardelli A, Rothwell J C, Thompson P D, Day B L, Marsden C D
MRC Human Movement and Balance Unit, Institute of Neurology, London.
J Neurol Neurosurg Psychiatry. 1989 Sep;52(9):1043-9. doi: 10.1136/jnnp.52.9.1043.
Rapid, self paced and self terminated elbow flexion movements were studied in a group of 10 patients with dystonia affecting the arms. The movements were slower and for small amplitude movements, more variable than those recorded in normal subjects. The duration of the first agonist burst was prolonged, even when compared with normal subjects deliberately moving slowly. Cocontraction of agonist and antagonist muscles during ballistic movements was common and may contribute to the bradykinesia. These findings are compared with similar studies of other diseases of the motor system. Unlike many other conditions which also reduce the speed of ballistic voluntary movements, the patients with dystonia in the present study showed a normal symmetry of acceleration and deceleration times. One interpretation of this finding is that aspects of the basic motor programmes are relatively preserved in this condition and account for the surprising retention of motor skills shown by some patients with dystonia.
对一组10名患有手臂肌张力障碍的患者进行了快速、自行调节节奏且自行终止的肘部屈曲运动研究。与正常受试者记录的运动相比，这些运动较慢，且对于小幅度运动而言，变化更大。即使与故意缓慢运动的正常受试者相比，首次主动肌爆发的持续时间也延长了。在弹道运动期间，主动肌和拮抗肌的共同收缩很常见，这可能导致运动迟缓。将这些发现与运动系统其他疾病的类似研究进行了比较。与许多其他也会降低弹道式自主运动速度的病症不同，本研究中的肌张力障碍患者在加速和减速时间上显示出正常的对称性。对这一发现的一种解释是，在这种情况下基本运动程序的某些方面相对保留，这解释了一些肌张力障碍患者表现出的令人惊讶的运动技能保留情况。
