Schrøder S A, Homøe P, Wagner N, Bardow A
Department of Otorhinolaryngology,Nordsjaellands University Hospital,Hillerod.
Department of Otorhinolaryngology and Maxillofacial Surgery,Zealand University Hospital,Koege.
J Laryngol Otol. 2017 Feb;131(2):162-167. doi: 10.1017/S002221511600966X. Epub 2016 Dec 15.
Saliva composition may affect sialolithiasis formation; thus, this study compared the salivary inorganic composition of sialolithiasis patients with that of healthy controls, and determined whether salivary inorganic composition changes after sialolithiasis surgery.
The study included 40 patients with sialolithiasis and 40 matched healthy controls. Patients were examined before and after sialolithiasis surgery; controls were examined once. Flow rate and the inorganic saliva composition in unstimulated whole saliva were assessed.
Patients' salivary flow prior to surgery was significantly lower compared to that of healthy controls, but equalised after surgery. Prior to surgery, patients' saliva exhibited higher concentrations of calcium, magnesium, phosphorous compared to that of healthy controls. The concentration of most ions remained high after sialolithiasis surgery.
Sialolithiasis patients had increased salivary concentrations of the ions that constitute the main inorganic phase of most sialoliths, and this may confer a risk for developing sialolithiasis.
唾液成分可能影响涎石病的形成；因此，本研究比较了涎石病患者与健康对照者的唾液无机成分，并确定涎石病手术后唾液无机成分是否发生变化。
本研究纳入40例涎石病患者和40例匹配的健康对照者。对患者在涎石病手术前后进行检查；对照者仅检查一次。评估未刺激全唾液的流速和无机成分。
手术前患者的唾液流速显著低于健康对照者，但手术后两者相等。手术前，患者唾液中的钙、镁、磷浓度高于健康对照者。涎石病手术后大多数离子的浓度仍保持较高水平。
涎石病患者唾液中构成大多数涎石主要无机相的离子浓度升高，这可能会增加患涎石病的风险。
