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2016 年更新版的 EULAR 早期关节炎管理建议。

2016 update of the EULAR recommendations for the management of early arthritis.

机构信息

Rheumatology Department, Lapeyronie Hospital, Montpellier University, UMR 5535, Montpellier, France.

Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology Center, Amsterdam and Zuyderland Medical Centre, Heerlen, The Netherlands.

出版信息

Ann Rheum Dis. 2017 Jun;76(6):948-959. doi: 10.1136/annrheumdis-2016-210602. Epub 2016 Dec 15.

Abstract

OBJECTIVES

Since the 2007 recommendations for the management of early arthritis have been presented, considerable research has been published in the field of early arthritis, mandating an update of the 2007 European League Against Rheumatism (EULAR) recommendations for management of early arthritis.

METHODS

In accordance with the 2014 EULAR Standardised Operating Procedures, the expert committee pursued an approach that was based on evidence in the literature and on expert opinion. The committee involved 20 rheumatologists, 2 patients and 1 healthcare professional representing 12 European countries. The group defined the focus of the expert committee and target population, formulated a definition of 'management' and selected the research questions. A systematic literature research (SLR) was performed by two fellows with the help of a skilled librarian. A set of draft recommendations was proposed on the basis of the research questions and the results of the SLR. For each recommendation, the categories of evidence were identified, the strength of recommendations was derived and the level of agreement was determined through a voting process.

RESULTS

The updated recommendations comprise 3 overarching principles and 12 recommendations for managing early arthritis. The selected statements involve the recognition of arthritis, referral, diagnosis, prognostication, treatment (information, education, pharmacological and non-pharmacological interventions), monitoring and strategy. Eighteen items were identified as relevant for future research.

CONCLUSIONS

These recommendations provide rheumatologists, general practitioners, healthcare professionals, patients and other stakeholders with an updated EULAR consensus on the entire management of early arthritis.

摘要

目的

自 2007 年提出早期关节炎管理建议以来,该领域已发表了大量研究,因此需要更新 2007 年欧洲抗风湿病联盟(EULAR)的早期关节炎管理建议。

方法

根据 2014 年 EULAR 标准操作程序,专家委员会采用了一种基于文献证据和专家意见的方法。该委员会由 20 名风湿病学家、2 名患者和 1 名代表 12 个欧洲国家的医疗保健专业人员组成。该小组定义了专家委员会的重点和目标人群,制定了“管理”的定义,并选择了研究问题。两名研究员在一名熟练的图书管理员的帮助下进行了系统文献检索(SLR)。根据研究问题和 SLR 的结果,提出了一套建议草案。对于每个建议,确定了证据类别,得出了建议的强度,并通过投票确定了共识水平。

结果

更新后的建议包括 3 个总体原则和 12 条管理早期关节炎的建议。选定的陈述涉及关节炎的识别、转诊、诊断、预后、治疗(信息、教育、药物和非药物干预)、监测和策略。确定了 18 个项目作为未来研究的重点。

结论

这些建议为风湿病学家、全科医生、医疗保健专业人员、患者和其他利益相关者提供了更新的 EULAR 共识,涵盖了早期关节炎的整个管理过程。

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