Mocan H, Murphy A V, Beattie T J, McAllister T A
Department of Nephrology, Royal Hospital for Sick Children, Glasgow.
Scott Med J. 1989 Aug;34(4):494-6. doi: 10.1177/003693308903400404.
Between 1979 and 1985, six of 26 patients undergoing continuous ambulatory peritoneal dialysis developed fungal peritonitis. All had received antibacterial therapy with cefamandole and/or netilmicin prior to the diagnosis. The causal organisms were Candida albicans (three), Candida glabrata (one), Cryptococcus laurentii (one) and Saccharomyces cerevisiae (one). Treatment comprised catheter removal preceded by antifungal drugs (flucytosine and/or amphotericin B) in four patients and catheter removal alone in two. All patients were transferred to haemodialysis and five of the six developed extensive intra-abdominal adhesions. The most prudent management of fungal peritonitis in children would seem to be early cannula removal.
1979年至1985年间，26例接受持续性非卧床腹膜透析的患者中有6例发生真菌性腹膜炎。所有患者在诊断前均接受了头孢孟多和/或奈替米星抗菌治疗。致病微生物为白色念珠菌（3例）、光滑念珠菌（1例）、罗伦隐球菌（1例）和酿酒酵母（1例）。4例患者在拔除导管前先使用抗真菌药物（氟胞嘧啶和/或两性霉素B），2例仅拔除导管。所有患者均转为血液透析，6例中有5例发生广泛的腹腔内粘连。儿童真菌性腹膜炎最谨慎的处理方法似乎是早期拔除套管。
