Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa.
Emerg Infect Dis. 2013 Jun;19(6):899-908. doi: 10.3201/eid1906.120543.
We aimed to estimate the global occurrence of zoonotic tuberculosis (TB) caused by Mycobacterium bovis or M. caprae infections in humans by performing a multilingual, systematic review and analysis of relevant scientific literature of the last 2 decades. Although information from many parts of the world was not available, data from 61 countries suggested a low global disease incidence. In regions outside Africa included in this study, overall median proportions of zoonotic TB of ≤1.4% in connection with overall TB incidence rates ≤71/100,000 population/year suggested low incidence rates. For countries of Africa included in the study, we multiplied the observed median proportion of zoonotic TB cases of 2.8% with the continental average overall TB incidence rate of 264/100,000 population/year, which resulted in a crude estimate of 7 zoonotic TB cases/100,000 population/year. These generally low incidence rates notwithstanding, available data indicated substantial consequences of this disease for some population groups and settings.
我们旨在通过对过去 20 年相关科学文献的多语言系统回顾和分析，估计由牛分枝杆菌或山羊分枝杆菌感染引起的人兽共患结核病（TB）的全球发病情况。尽管世界上许多地区的信息无法获得，但来自 61 个国家的数据表明全球疾病发病率较低。在所研究的非洲以外地区，与总体 TB 发病率≤71/100,000 人/年相关的总体兽源型 TB 的中位数比例≤1.4%，这表明发病率较低。对于纳入本研究的非洲国家，我们用观察到的 2.8%的兽源型 TB 病例中位数比例乘以大陆平均的 264/100,000 人/年的总体 TB 发病率，得出每年每 10 万人中有 7 例兽源型 TB 病例的粗略估计。尽管这些发病率通常较低，但现有数据表明，这种疾病对一些人群和环境造成了重大影响。
