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经颅直流电刺激在失语症康复中的应用:对采用无创脑刺激进行语言恢复的行为干预的系统评价。

Use of tDCS in Aphasia Rehabilitation: A Systematic Review of the Behavioral Interventions Implemented With Noninvasive Brain Stimulation for Language Recovery.

作者信息

Galletta Elizabeth E, Conner Peggy, Vogel-Eyny Amy, Marangolo Paola

机构信息

Rusk Rehabilitation, New York University/Langone Medical CenterProgram in Speech-Language-Hearing Sciences, Graduate Center, City University of New York.

Program in Speech-Language-Hearing Sciences, Lehman College, City University of New York.

出版信息

Am J Speech Lang Pathol. 2016 Dec 1;25(4S):S854-S867. doi: 10.1044/2016_AJSLP-15-0133.

DOI:10.1044/2016_AJSLP-15-0133
PMID:27997958
Abstract

PURPOSE

The purpose of this article is to review the behavioral treatments used in aphasia rehabilitation research that have been combined with transcranial direct current stimulation (tDCS). Although tDCS in aphasia treatment has shown promise, the results have not been conclusive, and their interpretation is further compounded by the heterogeneity of study characteristics. Because implementing a behavioral task during brain stimulation has been shown to be pivotal to the adjuvant effects of tDCS, we analyze the behavioral treatments that have been paired with tDCS.

METHOD

A computerized database search (PubMed) was completed to document and review aphasia treatment studies that combine behavioral treatment with noninvasive brain stimulation in the form of tDCS. Two authors reviewed each aphasia tDCS article published between 2008 and 2015 and evaluated (a) the behavioral interventions for aphasia that have been combined with tDCS, and (b) the methodological variables that may have influenced language outcomes in the tDCS aphasia literature.

CONCLUSIONS

A review of the behavioral treatments implemented in tDCS aphasia rehabilitation studies highlights several methodological considerations for future investigations. Impairment-focused and pragmatic treatments have been implemented in tDCS aphasia research studies. No one behavioral approach stands out as the best treatment to combine with tDCS for the promotion of language recovery.

摘要

目的

本文旨在综述失语症康复研究中与经颅直流电刺激(tDCS)相结合的行为治疗方法。尽管tDCS在失语症治疗中已显示出前景,但结果尚无定论,而且研究特征的异质性进一步加剧了对结果的解读难度。由于在脑刺激过程中实施行为任务已被证明是tDCS辅助作用的关键,因此我们分析了与tDCS配对的行为治疗方法。

方法

完成了一项计算机化数据库搜索(PubMed),以记录和综述将行为治疗与tDCS形式的无创脑刺激相结合的失语症治疗研究。两位作者对2008年至2015年间发表的每篇失语症tDCS文章进行了综述,并评估了(a)与tDCS相结合的失语症行为干预措施,以及(b)可能影响tDCS失语症文献中语言结果的方法学变量。

结论

对tDCS失语症康复研究中实施的行为治疗方法进行综述,突出了未来研究的几个方法学考虑因素。tDCS失语症研究中实施了以损伤为重点和务实的治疗方法。没有一种行为方法脱颖而出,成为与tDCS相结合促进语言恢复的最佳治疗方法。

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