Pilloni Giuseppina, Bikson Marom, Badran Bashar W, George Mark S, Kautz Steven A, Okano Alexandre Hideki, Baptista Abrahão Fontes, Charvet Leigh E
Department of Neurology, NYU Langone Health, New York, NY, United States.
Department of Biomedical Engineering, The City College of New York, New York, NY, United States.
Front Hum Neurosci. 2020 Nov 12;14:595567. doi: 10.3389/fnhum.2020.595567. eCollection 2020.
The coronavirus disease 19 (COVID-19) pandemic has resulted in the urgent need to develop and deploy treatment approaches that can minimize mortality and morbidity. As infection, resulting illness, and the often prolonged recovery period continue to be characterized, therapeutic roles for transcranial electrical stimulation (tES) have emerged as promising non-pharmacological interventions. tES techniques have established therapeutic potential for managing a range of conditions relevant to COVID-19 illness and recovery, and may further be relevant for the general management of increased mental health problems during this time. Furthermore, these tES techniques can be inexpensive, portable, and allow for trained self-administration. Here, we summarize the rationale for using tES techniques, specifically transcranial Direct Current Stimulation (tDCS), across the COVID-19 clinical course, and index ongoing efforts to evaluate the inclusion of tES optimal clinical care.
2019年冠状病毒病(COVID-19)大流行导致迫切需要开发和应用能够将死亡率和发病率降至最低的治疗方法。随着感染、由此引发的疾病以及通常较长的恢复期的特征不断被明确,经颅电刺激(tES)的治疗作用已成为有前景的非药物干预措施。tES技术在治疗一系列与COVID-19疾病及康复相关病症方面已展现出治疗潜力,并且在此期间对于心理健康问题增多的总体管理可能也具有相关性。此外,这些tES技术成本低廉、便于携带,且允许经过培训后自行操作。在此,我们总结了在COVID-19临床病程中使用tES技术,特别是经颅直流电刺激(tDCS)的基本原理,并列举了当前为评估将tES纳入最佳临床护理所做的努力。