催化对映选择性烯基芳基硼化反应。
Catalytic Enantioselective Arylboration of Alkenylarenes.
机构信息
Department of Chemistry, Indiana University, 800 E. Kirkwood Ave., Bloomington, IN, 47401, USA.
出版信息
Angew Chem Int Ed Engl. 2017 Jan 16;56(3):851-855. doi: 10.1002/anie.201609844. Epub 2016 Dec 21.
Abstract
A method for the catalytic enantioselective arylboration of alkenylarenes is disclosed. The reaction leads to the formation of 1,1-diarylalkanes that also incorporate an additional pinacol boronic ester which can be easily transformed to a variety of groups. The products are formed with excellent diastereoselectivities and enantioselectivities.
摘要
公开了一种烯基芳基烯烃的催化对映选择性芳基硼化方法。该反应导致 1,1-二芳基链烷的形成，其还掺入可容易转化为各种基团的额外频哪醇硼酸酯。产物以优异的非对映选择性和对映选择性形成。
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