Department of Chemistry, Indiana University , 800 East Kirkwood Avenue, Bloomington, Indiana 47405, United States.
J Am Chem Soc. 2018 Jan 10;140(1):159-162. doi: 10.1021/jacs.7b12160. Epub 2017 Dec 22.
A Ni-catalyzed method for arylboration is disclosed. The method allows for highly stereoselective arylboration of unactivated alkenes. The reactions utilize a simple Ni-catalyst and work with a broad range of alkenes and aryl bromides. The products represent useful intermediates for chemical synthesis due to the versatility of the C-B bond. Preliminary mechanistic details of the method are also disclosed.
公开了一种镍催化的芳基硼酸化方法。该方法允许对未活化的烯烃进行高度立体选择性的芳基硼酸化。该反应利用简单的镍催化剂,并与广泛的烯烃和芳基溴化物一起使用。由于 C-B 键的多功能性,这些产物代表了化学合成中有用的中间体。该方法的初步机理细节也被公开。