Chen Shuang, Jiang Hongmei, Wu Xiaosong, Fang Jun
College of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
College of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China; Hunan Province University Key Laboratory for Agricultural Biochemistry and Biotransformation, Hunan Agricultural University, Changsha 410128, China; Hunan CoInnovation Center for Ultilization of Botanical Functional Ingredients, Changsha 410128, China.
Mediators Inflamm. 2016;2016:9340637. doi: 10.1155/2016/9340637. Epub 2016 Nov 28.
In previous studies, abdominal obesity has been related to total low-grade inflammation and in some cases has resulted in insulin resistance and other metabolism related disorders such as diabetes. Quercetin is a polyphenol, which is a derivative of plants, and has been shown as well as in a few animal models to have several potential anti-inflammatory as well as anticarcinogenic applications. The substance has also been shown to aid in the attenuation of lipid peroxidation, platelet aggregation, and capillary permeability. However, further research is called for to gain a better understanding of how quercetin is able to provide these beneficial effects. This manuscript reviewed quercetin's anti-inflammatory properties in relation to obesity and type 2 diabetes.
在先前的研究中,腹部肥胖与全身性低度炎症有关,在某些情况下还会导致胰岛素抵抗以及其他与代谢相关的疾病,如糖尿病。槲皮素是一种多酚类物质,是植物的衍生物,在一些动物模型中已显示出具有多种潜在的抗炎和抗癌作用。该物质还被证明有助于减轻脂质过氧化、血小板聚集和毛细血管通透性。然而,需要进一步研究以更好地了解槲皮素如何产生这些有益效果。本手稿综述了槲皮素与肥胖和2型糖尿病相关的抗炎特性。