Sieg Emily P, Stepanyan Hayk, Payne Russell, Frauenhoffer Elizabeth, Specht Charles S, Langan Sara, Rizk Elias
Department of Neurosurgery, Penn State Hershey Medical Center.
Medical Student, Penn State College of Medicine.
Cureus. 2016 Nov 14;8(11):e876. doi: 10.7759/cureus.876.
Undifferentiated pleomorphic sarcoma is a histologic diagnosis based on cell morphology. These tumors are found throughout the body. They are rarely found in the central nervous system and almost never occur as a primary intraventricular tumor. We present the unusual case of a 68-year-old woman with an intraventricular undifferentiated pleomorphic sarcoma. We go on to discuss the clinical presentation, radiographic characteristics, and management paradigm for these rare lesions. Our patient presented with acute confusion, inability to balance a checkbook, and gait imbalance. CT and MRI demonstrated a 4 x 3.6 x 3.6 cm enhancing lesion in the left lateral ventricle abutting the foramen of Monro. Pathology revealed an undifferentiated pleomorphic sarcoma.
未分化多形性肉瘤是一种基于细胞形态学的组织学诊断。这些肿瘤可在全身各处发现。它们很少见于中枢神经系统，几乎从不作为原发性脑室内肿瘤发生。我们报告了一例68岁女性发生脑室内未分化多形性肉瘤的罕见病例。我们接着讨论这些罕见病变的临床表现、影像学特征及治疗模式。我们的患者表现为急性意识模糊、无法核对支票簿账目以及步态不稳。CT和MRI显示左侧脑室有一个4×3.6×3.6 cm的强化病变，毗邻孟氏孔。病理检查显示为未分化多形性肉瘤。
