Lorusso Domenica, Bria Emilio, Costantini Anna, Di Maio Massimo, Rosti Giovanni, Mancuso Annamaria
Fondazione IRCCS - Istituto Nazionale Tumori, Milan, Italy.
Medical Oncology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Eur J Cancer Care (Engl). 2017 Mar;26(2). doi: 10.1111/ecc.12618. Epub 2016 Dec 22.
Chemotherapy side effects (CSE) have a strong impact on patients' quality of life (QOL). To assess patient perceptions of CSE, their impact on QOL and doctor-patient communication regarding these aspects, a survey was conducted among Italian cancer patients. Patients at least 18 years of age, who received chemotherapy, were administered a dedicated questionnaire to assess their point of view on five domains: expectations about CSE and impact on QOL; doctor-patient communication about CSE; treatments to reduce the impact of CSE; sexual life; family relationships/activities and employment. A total of 761 patients participated. CSE had a considerable impact on patient QOL. Nausea/vomiting was the most feared adverse effect before initiating chemotherapy and the one most commonly experienced during treatment. Patients generally reported good doctor-patient communication regarding information about CSE. In almost all cases, the oncologists prescribed an antiemetic treatment, but the incidence of nausea/vomiting was high. Cancer and CSE severely affected sexual life, daily activities and employment. CSE had a strong negative impact on QOL. Good doctor-patient communication is essential. Improving antiemetic strategies may improve QOL. Doctors' ability to inform patients about delicate issues, such as the impact of CSE on sexual life, needs to be improved.
化疗副作用（CSE）对患者的生活质量（QOL）有很大影响。为了评估患者对CSE的看法、其对生活质量的影响以及医患在这些方面的沟通情况，对意大利癌症患者进行了一项调查。年龄至少18岁且接受化疗的患者填写了一份专门问卷，以评估他们在五个领域的观点：对CSE的期望及其对生活质量的影响；医患关于CSE的沟通；减轻CSE影响的治疗方法；性生活；家庭关系/活动和就业。共有761名患者参与。CSE对患者的生活质量有相当大的影响。恶心/呕吐是化疗开始前最令人恐惧的不良反应，也是治疗期间最常出现的不良反应。患者普遍表示在关于CSE的信息方面医患沟通良好。几乎在所有情况下，肿瘤学家都开了止吐药，但恶心/呕吐的发生率仍然很高。癌症和CSE严重影响了性生活、日常活动和就业。CSE对生活质量有强烈的负面影响。良好的医患沟通至关重要。改进止吐策略可能会提高生活质量。医生向患者告知诸如CSE对性生活的影响等敏感问题的能力有待提高。
