Guo Mengjiao, Hao Guangen, Wang Baohua, Li Ning, Li Rong, Wei Liangmeng, Chai Tongjie
College of Veterinary Medicine, Sino-German Cooperative Research Centre for Zoonosis of Animal Origin of Shandong Province, Shandong Agricultural UniversityTai'an, China; Collaborative Innovation Centre for the Origin and Control of Emerging Infectious Diseases of Taishan Medical CollegeTai'an, China.
College of Veterinary Medicine, Sino-German Cooperative Research Centre for Zoonosis of Animal Origin of Shandong Province, Shandong Agricultural University Tai'an, China.
Front Microbiol. 2016 Dec 8;7:1975. doi: 10.3389/fmicb.2016.01975. eCollection 2016.
Given the promising results of applying (.subtilis) as a probiotic in both humans and animals, the aim of this study was to systematically investigate the effects of on growth performance, immune response and disease resistance in Cherry Valley ducks. At 28 d post-hatch (dph), ducks fed a diet with weighed significantly more, had higher relative immune organ weights (e.g., bursa of Fabricius, thymus, and spleen), and exhibited greater villus heights, villus height to crypt depth ratios (duodenum and jejunum), and shallower crypt depths in the duodenum than controls fed a normal diet ( < 0.05). Moreover, the major pro-inflammatory factors and antiviral proteins, as measured in the thymus and the spleen, were higher at 28 dph in ducks fed probiotics than those of 14 dph. After 28 d of feeding, the ducks were challenged with () and novel duck reovirus (NDRV), and ducks fed achieved survival rates of 43.3 and 100%, respectively, which were significantly greater than the control group's 20 and 83.3%. Altogether, diets with can improve Cherry Valley ducks' growth performance, innate immune response, and resistance against and NDRV.
鉴于将枯草芽孢杆菌作为益生菌应用于人和动物均取得了有前景的结果，本研究的目的是系统地研究枯草芽孢杆菌对樱桃谷鸭生长性能、免疫反应和抗病能力的影响。在孵化后28天（dph），饲喂含枯草芽孢杆菌日粮的鸭子体重显著更重，相对免疫器官重量更高（如法氏囊、胸腺和脾脏），并且与饲喂正常日粮的对照组相比，十二指肠绒毛高度更高、十二指肠和空肠的绒毛高度与隐窝深度比值更大，十二指肠隐窝深度更浅（P<0.05）。此外，在胸腺和脾脏中检测到的主要促炎因子和抗病毒蛋白，在28 dph时，饲喂益生菌的鸭子比14 dph时更高。饲喂28天后，用鸭疫里默氏菌（RA）和新型鸭呼肠孤病毒（NDRV）对鸭子进行攻毒，饲喂枯草芽孢杆菌的鸭子存活率分别为43.3%和100%，显著高于对照组的20%和83.3%。总之，含枯草芽孢杆菌的日粮可改善樱桃谷鸭的生长性能、先天免疫反应以及对RA和NDRV的抵抗力。
