葡萄膜炎患者治疗后视觉功能的变化：来自尼泊尔的经验。
Change in Visual Function in Uveitis Patients after Treatment: An Experience from Nepal.
机构信息
a Rapti Eye Hospital , Dang , Nepal.
b Ophthalmology, B. P. Koirala Lions Centre for Ophthalmic Studies , Tribhuvan University, Institute of Medicine , Kathmandu , Nepal.
出版信息
Ocul Immunol Inflamm. 2018;26(5):747-752. doi: 10.1080/09273948.2016.1264610. Epub 2016 Dec 23.
PURPOSE
To assess the change in visual function in uveitis patients after treatment.
MATERIALS AND METHODS
This one and a half year prospective study was conducted among 180 new uveitis patients. A questionnaire was used to assess the visual function in uveitis cases and analysis of effect size change was also done.
RESULTS
The male to female ratio was 1.3:1. The mean vision at presentation was 0.49 logMAR units, which improved to 0.39 logMAR units and 0.35 logMAR units by the 1st and 4th week but deteriorated to 0.62 logMAR units at the 6th week. Anterior uveitis and posterior uveitis patients had significant improvement (p≤0.001) in all three scales but panuveitis and intermediate uveitis had significant improvement (p<0.05) in two scales. The effect size showed small to large change in all three scales.
CONCLUSIONS
Visual function is adversely affected by uveitis, which can be improved after treatment.
目的
评估葡萄膜炎患者治疗后的视觉功能变化。
材料和方法
这是一项为期一年半的前瞻性研究，共纳入 180 例新诊断的葡萄膜炎患者。采用问卷调查评估葡萄膜炎患者的视觉功能，并进行效应量变化分析。
结果
男女比例为 1.3:1。就诊时的平均视力为 0.49 logMAR 单位，第 1 周和第 4 周分别改善至 0.39 logMAR 单位和 0.35 logMAR 单位，但第 6 周时恶化至 0.62 logMAR 单位。前葡萄膜炎和后葡萄膜炎患者在所有三个量表中均有显著改善（p≤0.001），但全葡萄膜炎和中间葡萄膜炎在两个量表中有显著改善（p<0.05）。所有三个量表的效应量均显示出从小到中等的变化。
结论
葡萄膜炎会对视觉功能产生不利影响，但治疗后可以得到改善。
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