Venkataraman Arvind, Rathinam S R
Aravind Eye Hospital and Postgraduate Institute of Ophthalmology Madurai, India.
Indian J Ophthalmol. 2008 Jul-Aug;56(4):307-12. doi: 10.4103/0301-4738.39662.
To study the effect of treatment on vision-related quality of life (VR-QOL) in uveitis patients.
Interviewer-administered questionnaire-based evaluation of visual function and VR-QOL in Tamil-speaking adult patients with active uveitis at presentation and follow-up by the same interviewer.
Ninety-eight patients participated in this study. There was a statistically significant improvement in VR-QOL in all the scales following treatment ( P < 0.001). Patients with chronic uveitis showed better improvement upon treatment than patients with acute uveitis. The visual symptoms scale showed moderate gains following treatment (effect size 0.56). Persons with bilateral disease had poorer mean scores compared to those with unilateral disease. Visual acuity was closely correlated with VR-QOL scores.
The VR-QOL measurement has shown that it is sensitive to demonstrate the problems of patients with uveitis irrespective of their demographic profile. The scores improved significantly in patients with uveitis following treatment and have shown close correlation to visual acuity thus demonstrating that VR-QOL is effective in assessing the response to treatment.
研究治疗对葡萄膜炎患者视力相关生活质量(VR-QOL)的影响。
由访谈者对泰米尔语成年活动性葡萄膜炎患者进行基于问卷的视觉功能和VR-QOL评估,初诊时及随访时由同一访谈者进行。
98名患者参与了本研究。治疗后所有量表的VR-QOL均有统计学显著改善(P < 0.001)。慢性葡萄膜炎患者治疗后的改善情况优于急性葡萄膜炎患者。视觉症状量表治疗后有中度改善(效应量0.56)。双侧患病者的平均得分低于单侧患病者。视力与VR-QOL得分密切相关。
VR-QOL测量表明,无论患者的人口统计学特征如何,它都能敏感地显示葡萄膜炎患者的问题。葡萄膜炎患者治疗后得分显著改善,且与视力密切相关,因此表明VR-QOL在评估治疗反应方面是有效的。