Stanek Agata, Sieroń-Stołtny Karolina, Romuk Ewa, Cholewka Armand, Wielkoszyński Tomasz, Cieślar Grzegorz, Kwiatek Sebastian, Sieroń Aleksander, Kawczyk-Krupka Aleksandra
Department of Internal Medicine, Angiology and Physical Medicine, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Poland.
Department of Physical Medicine, Chair of Physiotherapy, School of Health Sciences in Katowice, Medical University of Silesia, Poland.
Adv Clin Exp Med. 2016 Nov-Dec;25(6):1281-1291. doi: 10.17219/acem/65980.
Whole-body cryostimulation (WBC) is the therapeutic exposure of the total human body (without underwear) to a very low temperature (below -100°C) for 120-180 s. Currently, WBC is used more frequently not only in the treatment of patients suffering from various diseases, but also by healthy people as a wellness method.
The aim of this research is to evaluate the impact of WBC procedures on oxidative stress parameters in healthy men.
The study involved 32 healthy male subjects who were randomly divided into 2 groups: 16 men exposed to WBC procedures with subsequent kinesiotherapy (WBC group) and 16 men exposed only to kinesiotherapy procedures (KT group). Depending on the group, the subjects were exposed to 10 daily WBC procedures lasting 3 min, with a subsequent 60-min of kinesiotherapy, or exclusively to kinesiotherapy. In subjects from both groups, a day before the beginning of a cycle of treatment and a day after its completion, the level of selected indicators of oxidative stress and non-enzymatic antioxidants, as well as the activity of antioxidant enzymes in serum, plasma and erythrocyte lysates were determined.
In the WBC group subjects, we recorded a statistically significant decrease in the concentrations of most of the parameters of oxidative stress with an accompanying increase in plasma concentrations of non-enzymatic antioxidants (total antioxidant status and uric acid). We recorded no significant changes in the activities of antioxidant enzymes (plasma total superoxide dismutase (SOD) and its isoenzymes SOD-Mn and SOD-ZnCu, erythrocyte catalase, glutathione peroxidase and glutathione reductase).
The results we obtained confirmed that WBC decreases oxidative stress in healthy men.
全身冷冻刺激（WBC）是将整个人体（不穿内衣）暴露于极低温度（低于-100°C）下120 - 180秒的治疗方法。目前，WBC不仅更频繁地用于治疗各种疾病的患者，也被健康人用作一种保健方法。
本研究的目的是评估WBC程序对健康男性氧化应激参数的影响。
该研究纳入32名健康男性受试者，随机分为2组：16名男性接受WBC程序并随后进行运动疗法（WBC组），16名男性仅接受运动疗法程序（KT组）。根据分组情况，受试者每天接受10次持续3分钟的WBC程序，随后进行60分钟的运动疗法，或仅接受运动疗法。在两组受试者中，在治疗周期开始前一天和结束后一天，测定氧化应激和非酶抗氧化剂的选定指标水平，以及血清、血浆和红细胞裂解物中抗氧化酶的活性。
在WBC组受试者中，我们记录到大多数氧化应激参数的浓度有统计学意义的下降，同时血浆中非酶抗氧化剂（总抗氧化状态和尿酸）的浓度增加。我们未记录到抗氧化酶活性（血浆总超氧化物歧化酶（SOD）及其同工酶SOD-Mn和SOD-ZnCu、红细胞过氧化氢酶、谷胱甘肽过氧化物酶和谷胱甘肽还原酶）有显著变化。
我们获得的结果证实WBC可降低健康男性的氧化应激。
