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维生素D:肌肉骨骼健康。

Vitamin D: Musculoskeletal health.

作者信息

Bhattoa Harjit Pal, Konstantynowicz Jerzy, Laszcz Natalia, Wojcik Marek, Pludowski Pawel

机构信息

Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98, H-4032, Debrecen, Hungary.

Department of Pediatric Rheumatology, Immunology, and Metabolic Bone Diseases, Medical University of Bialystok, ul. Waszyngtona 17, 15-274, Bialystok, Poland.

出版信息

Rev Endocr Metab Disord. 2017 Sep;18(3):363-371. doi: 10.1007/s11154-016-9404-x.

Abstract

Perhaps the role of Vitamin D supplementation has been most exhaustively studied in calcium absorption, skeletal wellbeing, muscular potency, balance and risk of falling. Nonetheless, new data has emerged and the recent research on sarcopenia makes the topic increasingly interesting. Given the socioeconomic burden of the musculoskeletal consequences of hypovitaminosis D it is vital to keep abreast with the latest literature in the field. The recommended Vitamin D supplementation dose should suffice to increase the serum 25 hydroxyvitamin D level to 30 ng/mL (75 nmol/L) and this level should be optimally maintained with a maintenance dose, particularly for those diagnosed with osteoporosis.

摘要

维生素D补充剂的作用可能在钙吸收、骨骼健康、肌肉力量、平衡和跌倒风险方面得到了最为详尽的研究。尽管如此,新的数据已经出现,最近关于肌肉减少症的研究使这个话题越来越有趣。鉴于维生素D缺乏症对肌肉骨骼造成的社会经济负担,紧跟该领域的最新文献至关重要。推荐的维生素D补充剂量应足以将血清25羟维生素D水平提高到30纳克/毫升(75纳摩尔/升),并且应以维持剂量最佳地维持该水平,特别是对于那些被诊断患有骨质疏松症的人。

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