Chung S, Wang X, Lui Y W
From the Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York.
AJNR Am J Neuroradiol. 2017 Apr;38(4):726-728. doi: 10.3174/ajnr.A5053. Epub 2016 Dec 29.
The effect of T1 signal on FSL voxel-based morphometry modulated GM density and FreeSurfer cortical thickness is explored. The techniques rely on different analyses, but both are commonly used to detect spatial changes in GM. Standard pipelines show FSL voxel-based morphometry is sensitive to T1 signal alterations within a physiologic range, and results can appear discordant between FSL voxel-based morphometry and FreeSurfer cortical thickness. Care should be taken in extrapolating results to the effect on brain volume.
探讨了T1信号对基于FSL体素形态计量学调节的灰质密度和FreeSurfer皮质厚度的影响。这些技术依赖于不同的分析方法,但两者都常用于检测灰质的空间变化。标准流程表明,基于FSL体素的形态计量学对生理范围内的T1信号改变敏感,并且基于FSL体素的形态计量学和FreeSurfer皮质厚度之间的结果可能不一致。在将结果外推至对脑容量的影响时应谨慎。