Hjelm E, Lundell-Etherden I
Department of Clinical Bacteriology, University of Uppsala, Sweden.
APMIS. 1989 Oct;97(10):935-40. doi: 10.1111/j.1699-0463.1989.tb00501.x.
Extracellular products from Staphylococcus saprophyticus were isolated and tested for their effect on the lymphoproliferative activity of con A and LPS and on the growth of human lymphocytes. The stimulatory effects of con A or LPS were not affected but a T-cell mitogenic activity was noted after 5 days of incubation. The extracellular material was separated by gel chromatography and the mitogenic activity was shown to be located to the protein fraction.
分离出腐生葡萄球菌的细胞外产物,并测试其对刀豆球蛋白A(Con A)和脂多糖(LPS)的淋巴细胞增殖活性以及对人淋巴细胞生长的影响。Con A或LPS的刺激作用未受影响,但在孵育5天后观察到一种T细胞促有丝分裂活性。通过凝胶色谱法分离细胞外物质,结果表明促有丝分裂活性位于蛋白质部分。