Shen Shiwei, Lu Yun, Dang Yingjie, Qi Huajin, Shen Zhenhai, Wu Liuxin, Li Feng, Yang Chengjian, Qiang Dongchang, Yang Yan, Shui Kedong, Bao Yanying
Wuxi No.2 People's Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214002, China.
The Taihu Rehabilitation Hospital of Jiangsu Province, Wuxi, Jiangsu 214086, China.
Int J Cardiol. 2017 Mar 1;230:1-5. doi: 10.1016/j.ijcard.2016.12.132. Epub 2016 Dec 21.
The aim of this study was to examine the correlation between aerobic exercise and the atherogenic index of plasma (AIP) in middle-aged Chinese men stratified by body weight.
A cross-sectional study, which recruited 26,701 middle-aged Chinese men undergoing health examinations in our hospital from 1st January 2014 to 30th June 2015 was performed, and the associations between body weight and AIP, and aerobic exercise and AIP were evaluated.
The mean AIP levels were -0.016±0.305, 0.138±0.3171 and 0.211±0.3243 in normal weight, overweight and obese subjects, respectively, and appeared to rise with body weight. Significantly higher AIP levels were observed in subjects with a weekly aerobic exercise period ≥90min than in those with a weekly aerobic exercise period <90min, and the mean AIP levels were -0.038±0.3015, 0.117±0.3182 and 0.192±0.3209, and were 0.003±0.3067, 0.156±0.3149 and 0.225±0.3263 in normal weight, overweight and obese men with a weekly aerobic exercise period ≥90min and <90min, respectively. In addition, aerobic exercise significantly reduced AIP after adjustment for age, systolic blood pressure, diastolic blood pressure, body mass index (BMI), fasting blood glucose and uric acid.
Lowering body weight and/or increasing aerobic exercise time may reduce AIP, and lowering body weight results in a greater reduction in AIP than aerobic exercise. Weight control combined with increased aerobic exercise time may cause a synergistic effect on the reduction of AIP.
本研究旨在探讨按体重分层的中国中年男性有氧运动与血浆致动脉粥样硬化指数（AIP）之间的相关性。
进行了一项横断面研究，纳入了2014年1月1日至2015年6月30日在我院接受健康检查的26701名中国中年男性，评估体重与AIP以及有氧运动与AIP之间的关联。
正常体重、超重和肥胖受试者的平均AIP水平分别为-0.016±0.305、0.138±0.3171和0.211±0.3243，且似乎随体重增加而升高。每周有氧运动时间≥90分钟的受试者的AIP水平显著高于每周有氧运动时间<90分钟的受试者，每周有氧运动时间≥90分钟的正常体重、超重和肥胖男性的平均AIP水平分别为-0.038±0.3015、0.117±0.3182和0.192±0.3209，每周有氧运动时间<90分钟的分别为0.003±0.3067、0.156±0.3149和0.225±0.3263。此外，在调整年龄、收缩压、舒张压、体重指数（BMI）、空腹血糖和尿酸后，有氧运动显著降低了AIP。
减轻体重和/或增加有氧运动时间可能会降低AIP，且减轻体重比有氧运动能使AIP降低得更多。体重控制与增加有氧运动时间相结合可能对降低AIP产生协同作用。
