Ding Zenghui, Chen Yanyan, Xu Yang, Zhou Xu, Xu Yubing, Ma Zuchang, Sun Yining
Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, Anhui, China; Department of Automation, University of Science and Technology of China, Hefei, Anhui, China.
Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, Anhui, China.
J Clin Densitom. 2018 Jan-Mar;21(1):83-90. doi: 10.1016/j.jocd.2016.11.001. Epub 2016 Dec 27.
Identifying modifiable factors that influence bone status during adulthood to maximize bone quality is a potential primary strategy in the prevention of osteoporosis in later life. We investigated the impact of body height, body weight, body mass index, and body composition on calcaneal bone characteristics as measured with quantitative ultrasound in 441 Chinese adults (238 women) aged 20-55 yr from the middle areas of China. Body composition, including fat-free mass (FFM), muscle mass, and fat mass were obtained by bioelectrical impedance analysis. Bivariate correlation analysis demonstrated a significant negative correlation between age and broadband ultrasound attenuation (BUA), speed of sound (SOS), and stiffness index (SI) both in men (r = -0.177, p < 0.05; r = -0.499, p < 0.001; r = -0.530, p < 0.001, respectively) and women (r = -0.344, p < 0.001; r = -0.336, p < 0.001; r = -0.369, p < 0.001, respectively). Body height, body weight, FFM, and muscle mass had positive correlations with BUA, SOS, and SI in both genders, with FFM having the strongest correlation with BUA, SOS, and SI in men (r = 0.351, p < 0.001; r = 0.391, p < 0.001; r = 0.406, p < 0.001, respectively) and women (r = 0.331, p < 0.001; r = 0.288, p < 0.001; r = 0.324, p < 0.001, respectively). Fat mass had a positive correlation with BUA (r = 0.331, p < 0.001), SOS (r = 0.288, p < 0.001), and SI (r = 0.324, p < 0.001) in women, which was not found in men. Multivariate regression analysis revealed that, in both genders, FFM was a positive predictor for all 3 quantitative ultrasound variables.
确定成年期影响骨骼状态的可改变因素以最大化骨质量，是预防晚年骨质疏松症的一项潜在主要策略。我们调查了身高、体重、体重指数和身体成分对441名年龄在20 - 55岁的中国中部地区成年人（238名女性）跟骨骨特征的影响，这些特征通过定量超声测量。身体成分，包括去脂体重（FFM）、肌肉量和脂肪量，通过生物电阻抗分析获得。双变量相关分析表明，年龄与宽带超声衰减（BUA）、声速（SOS）和硬度指数（SI）之间在男性（r = -0.177，p < 0.05；r = -0.499，p < 0.001；r = -0.530，p < 0.001）和女性（r = -0.344，p < 0.001；r = -0.336，p < 0.001；r = -0.369，p < 0.001）中均呈显著负相关。身高、体重、FFM和肌肉量在两性中与BUA、SOS和SI均呈正相关，其中FFM与男性（r = 0.351，p < 0.001；r = 0.391，p < 0.001；r = 0.406，p < 0.001）和女性（r = 0.331，p < 0.001；r = 0.288，p < 0.001；r = 0.324，p < 0.001）的BUA、SOS和SI的相关性最强。脂肪量在女性中与BUA（r = 0.331，p < 0.001）、SOS（r = 0.288，p < 0.001）和SI（r = 0.324，p < 0.
