Kamdem Félicité, Lemogoum Daniel, Doualla Marie-Solange, Kemta Lepka Fernando, Temfack Elvis, Ngo Nouga Yvette, Kenmegne Caroline, Luma Henry, Hermans Michel P
Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.
Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
J Clin Hypertens (Greenwich). 2017 May;19(5):519-523. doi: 10.1111/jch.12959. Epub 2017 Jan 2.
The authors assessed the frequency of glucose homeostasis abnormalities among 839 Cameroonians with newly diagnosed hypertension (mean age: 50.8±11 years; 49.9% female) in a cross-sectional survey conducted at the Douala General Hospital, Douala, Cameroon. In all participants, blood pressure, fasting plasma glucose (FPG), and lipids were recorded. Impaired fasting glycemia was described as an FPG level between 100 and 125 mg/dL and provisional diabetes as an FPG level ≥126 mg/dL. The FPG was 101±30 mg/dL. The overall proportion of abnormal glucose homeostasis was 38.3%, while 7.7% of patients (n=65) had known diabetes. A total of 23.7% (n=199) had impaired fasting glycemia and 6.8% (n=57) had provisional diabetes. Multivariable logistic regression revealed that male sex (odds ratio [OR], 1.53; 95% confidence interval [CI], 1.15-2.06), age older than 55 years (OR, 1.55; 95% CI, 1.15-2.09), and low-density lipoprotein cholesterol >1 g/L (OR, 1.34; 95% CI, 1.00-1.82) were independently associated with abnormal glucose homeostasis (all P<.05). Glucose homeostasis abnormalities are highly prevalent among Cameroonian patients with newly diagnosed hypertension.
在喀麦隆杜阿拉总医院进行的一项横断面调查中，作者评估了839名新诊断为高血压的喀麦隆人（平均年龄：50.8±11岁；49.9%为女性）中葡萄糖稳态异常的发生率。记录了所有参与者的血压、空腹血糖（FPG）和血脂。空腹血糖受损被定义为FPG水平在100至125mg/dL之间，临时糖尿病为FPG水平≥126mg/dL。FPG为101±30mg/dL。葡萄糖稳态异常的总体比例为38.3%，而7.7%的患者（n=65）患有已知糖尿病。共有23.7%（n=199）的患者空腹血糖受损，6.8%（n=57）的患者患有临时糖尿病。多变量逻辑回归显示，男性（比值比[OR]，1.53；95%置信区间[CI]，1.15-2.06）、年龄大于55岁（OR，1.55；95%CI，1.15-2.09）和低密度脂蛋白胆固醇>1g/L（OR，1.34；95%CI，1.00-1.82）与葡萄糖稳态异常独立相关（所有P<.05）。葡萄糖稳态异常在新诊断为高血压的喀麦隆患者中非常普遍。
