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[持续气道正压通气治疗对阻塞性睡眠呼吸暂停低通气综合征患者抑郁、焦虑及感知应激水平的影响]

[Effect of Continuous Positive Airway Pressure Treatment on Depression, Anxiety and Perceived Stress Levels in Patients with Obstructive Sleep Apnea Syndrome].

作者信息

Çelik Mustafa, Sarıkaya Yasin, Acar Mustafa, Kalenderoğlu Aysun, Doğan Sedat, Kaskalan Emin, Karataş Mehmet

出版信息

Turk Psikiyatri Derg. 2016 Winter;27(4):244-250.

PMID:28046193
Abstract

OBJECTIVE

The aim of this study is to determine the effects of continuous positive airway pressure (CPAP) treatment on depression, anxiety, and perceived stress levels and to identify factors predictive of treatment efficacy in patients with obstructive sleep apnea syndrome (OSAS).

METHOD

This study included 51 patients admitted to the Adiyaman University Medical School Otorhinolaryngology Department or Eskisehir Yunus Emre State Hospital between January and September 2014 with one or more complaints including snoring, excessive daytime sleepiness, or apnea witnessed by the partner. Diagnosis of OSAS was made by polysomnography and CPAP treatment was initiated. Depression levels were assessed in all study subjects using the Hospital Anxiety and Depression Scale (HADS) at the start of treatment and at 3 months. Anxiety levels were assessed using both the HADS and the State and Trait Anxiety Inventory (STAI), and perceived stress level was assessed using the Perceived Stress Questionnaire (PSQ).

RESULTS

After CPAP treatment, we observed significant decreases in both the Depression and Anxiety Subscales of the HADS, in the Trait Anxiety subscale of the STAI, and in the PSQ. An evaluation of the initial parameters that predict improvements in these scales revealed that snoring time predicted decreases in all scale scores.

CONCLUSION

In OSAS patients CPAP treatment has positive effects on psychological parameters like depression, anxiety, and perceived stress. We suggest that possible psychogenic benefits should be considered when deciding to start CPAP treatment, particularly in patients with pronounced and extended snoring who may also have social problems.

摘要

目的

本研究旨在确定持续气道正压通气(CPAP)治疗对阻塞性睡眠呼吸暂停综合征(OSAS)患者抑郁、焦虑和感知压力水平的影响,并确定预测治疗效果的因素。

方法

本研究纳入了2014年1月至9月期间入住阿迪亚曼大学医学院耳鼻喉科或埃斯基谢希尔尤努斯·埃姆雷州立医院的51例患者,这些患者有一项或多项主诉,包括打鼾、日间过度嗜睡或配偶目睹的呼吸暂停。通过多导睡眠图诊断OSAS并开始CPAP治疗。在治疗开始时和3个月时,使用医院焦虑抑郁量表(HADS)对所有研究对象的抑郁水平进行评估。使用HADS和状态-特质焦虑量表(STAI)评估焦虑水平,使用感知压力问卷(PSQ)评估感知压力水平。

结果

CPAP治疗后,我们观察到HADS抑郁和焦虑分量表、STAI特质焦虑分量表以及PSQ均显著下降。对预测这些量表改善情况的初始参数进行评估后发现,打鼾时间可预测所有量表得分的下降。

结论

在OSAS患者中,CPAP治疗对抑郁、焦虑和感知压力等心理参数有积极影响。我们建议,在决定开始CPAP治疗时,应考虑可能的心理益处,尤其是对于打鼾明显且持续时间较长、可能还存在社会问题的患者。

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